CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10007
Family Name Mitogen-activated protein kinase kinase kinase 8 and Dual specificity mitogen-activated protein kinase kinase 1 inhibitor AGN-PC-00SQQE family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00163209 Functional Category Bioactive
Superfamily Aurora kinase A and Luciferin 4-monooxygenase Binder Superfamily
Class Class 1154

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
GDC-0349 family 44 77
JAK Inhibitor Momelotinib Family 33 83
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Amine oxidase [flavin-containing] A Inhibitor 3-benzyl-n-(2-mo... 2 3
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Ephrin type-B receptor 4 ligand SureCN3289519 family 4 2
Epidermal growth factor receptor ligand pyrido[4,3-d]pyrimidin... 11 0
Transient receptor potential cation channel subfamily V member... 4 0
Metabotropic glutamate receptor 1 ligand AGN-PC-00FV3S family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

38958 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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