CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10012
Family Name Adenosine receptor A2b ligand 2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)pyridin-2-yl]oxy-N-(4-fluorophenyl)acetamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00399045 Functional Category Bioactive
Superfamily and Serine/threonine-protein kinase TBK1 Binder Superfamily
Class Class 227

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand KW-6002 Family 18 195
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Adenosine receptor A1 and Adenosine receptor A2b ligand 3-meth... 7 19
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-[4-[... 12 15
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
Adenosine receptor A2b and Adenosine receptor A1 ligand MRS 17... 10 0
Histamine H3 receptor ligand SureCN7251693 family 3 1
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-09ODY0 ... 2 5
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9RSG ... 6 5
Adenosine receptor A1 and Adenosine receptor A3 ligand SureCN5... 3 1
Adenosine receptor A3 ligand (2Z)-2-(5-methoxy-2-methyl-1H-pyr... 8 4
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
Adenosine receptor A2b and Adenosine receptor A1 ligand (8Z)-8... 3 33
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 8 4
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... 2 8
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 7 11
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 8-[(6,7... 6 8
Collagenase 3 inhibitor 5-[4-[4-(1H-benzimidazol-2-yl)phenoxy]... 3 0
Collagenase 3 inhibitor 1-[6-[4-(1H-benzimidazol-2-yl)phenoxy]... 3 0
Adenosine receptor A2b and Adenosine receptor A1 ligand N-(1,3... 2 7
Adenosine receptor A1 and Adenosine receptor A2b ligand (2,5-d... 2 0
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiest... 7 0
Adenosine receptor A2b and Adenosine receptor A1 ligand N-(3,4... 1 8
Cholecystokinin receptor type A ligand AGN-PC-077L8J family 22 2
Hepatocyte growth factor receptor ligand 4-pyridone analogue, ... 8 0
Adenosine receptor A2b and Adenosine receptor A1 ligand [4-(2,... 6 15
Cholecystokinin receptor type A ligand AGN-PC-077KXF family 2 0
Adenosine receptor A2b and Adenosine receptor A2a ligand 1-eth... 5 2
Adenosine receptor A1 and Adenosine receptor A2b ligand N-[2-[... 2 1
Adenosine receptor A2b ligand (8Z)-8-[2-methyl-5-[2-(4-methylp... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00399045 CHEMBL199249 Bioactive 2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)pyridin-2-yl]oxy-N-(4-fluorophenyl)acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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