CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10032
Family Name Mitogen-activated protein kinase 14 inhibitor AGN-PC-044QVW family
No. of Seeds 10 No. of Other Members 1
Family Centroid CFAMM00399117 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 and Melanin-concentrating hormone receptor 1 Binder Superfamily
Class Class 3154

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
P2X purinoceptor 7 inhibitor SureCN3726471 family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-088GOO family 3 0
P2X purinoceptor 7 inhibitor SureCN3721807 family 3 0
Mitogen-activated protein kinase 14 inhibitor 5-(2-chloropheny... 1 0


External ID

Functional Category

Molecule Name

CFAMM00399122 CHEMBL199680 Bioactive AGN-PC-044QXM
CFAMM00399115 CHEMBL199593 Bioactive 7-(1-tert-butyl-3,6-dihydro-2H-pyridin-4-yl)-5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)quinolin-2-one
CFAMM00399121 CHEMBL356125 Bioactive AGN-PC-03T1YI
CFAMM00399114 CHEMBL199484 Bioactive AGN-PC-044QWH
CFAMM00399120 CHEMBL380806 Bioactive AGN-PC-044QW9
CFAMM00399113 CHEMBL199701 Bioactive AGN-PC-044R0S
CFAMM00399119 CHEMBL200093 Bioactive AGN-PC-044QWA
CFAMM00399118 CHEMBL199679 Bioactive AGN-PC-00E3P9
CFAMM00399117 CHEMBL381632 Bioactive AGN-PC-044QVW
CFAMM00399123 CHEMBL369989 Bioactive AGN-PC-075YNM

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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