CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10056
Family Name Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,4R,5R)-5-[2-chloro-6-(methylamino)purin-9-yl]-N-cyclopropyl-3,4-dihydroxythiolane-2-carboxamide family
No. of Seeds 16 No. of Other Members 6
Family Centroid CFAMM00399268 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A3 Binder Superfamily 8
Class Class 4759

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
Adenosine receptor A2a Ligand Atl-146e Family 33 94
P2Y purinoceptor 12 Inhibitor Ar-c69931 Mx Family 10 18
TG-C family 11 208
Histamine N-methyltransferase Inhibitor S-adenosyl-l-homocyste... 2 3
cAMP-dependent protein kinase type I-alpha regulatory subunit ... 12 0
Adenosine receptor A1 ligand CHEMBL258759 family 2 3
Adenosine receptor A1 and Adenosine receptor A2b ligand (2R,3R... 9 0
Adenosine receptor A3 and Adenosine receptor A2a ligand (2R,3R... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00399259 CHEMBL201427 Bioactive (2S,3S,4R,5R)-5-[2-chloro-6-(methylamino)purin-9-yl]-N-(cyclopropylmethyl)-3,4-dihydroxythiolane-2-carboxamide
CFAMM00399258 CHEMBL381408 Bioactive (2S,3S,4R,5R)-5-[2-chloro-6-(cyclopentylamino)purin-9-yl]-3,4-dihydroxy-N-methylthiolane-2-carboxamide
CFAMM00399251 CHEMBL606630 Bioactive (2S,3S,4R,5R)-N-cyclobutyl-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]thiolane-2-carboxamide
CFAMM00399264 CHEMBL201706 Bioactive (2S,3S,4R,5R)-5-[2-chloro-6-(methylamino)purin-9-yl]-3,4-dihydroxy-N-methylthiolane-2-carboxamide
CFAMM00399257 CHEMBL595569 Bioactive (2S,3S,4R,5R)-N-cyclopentyl-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]thiolane-2-carboxamide
CFAMM00399250 CHEMBL200184 Bioactive (2S,3S,4R,5R)-5-[2-chloro-6-(cyclopropylamino)purin-9-yl]-3,4-dihydroxy-N-methylthiolane-2-carboxamide
CFAMM00399263 CHEMBL594619 Bioactive (2S,3S,4R,5R)-N-(cyclopropylmethyl)-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]thiolane-2-carboxamide
CFAMM00399256 CHEMBL203357 Bioactive (2S,3S,4R,5R)-5-(6-amino-2-chloropurin-9-yl)-3,4-dihydroxy-N-methylthiolane-2-carboxamide
CFAMM00399249 CHEMBL608680 Bioactive (2S,3S,4R,5R)-3,4-dihydroxy-N-methyl-5-[6-(methylamino)purin-9-yl]thiolane-2-carboxamide
CFAMM00399255 CHEMBL202189 Bioactive (2S,3S,4R,5R)-5-[2-chloro-6-(cyclopentylamino)purin-9-yl]-N-ethyl-3,4-dihydroxythiolane-2-carboxamide
CFAMM00399268 CHEMBL199877 Bioactive (2S,3S,4R,5R)-5-[2-chloro-6-(methylamino)purin-9-yl]-N-cyclopropyl-3,4-dihydroxythiolane-2-carboxamide
CFAMM00399248 CHEMBL201324 Bioactive (2S,3S,4R,5R)-5-[2-chloro-6-(methylamino)purin-9-yl]-3,4-dihydroxy-N-(3-methylbutyl)thiolane-2-carboxamide
CFAMM00399254 CHEMBL200705 Bioactive (2S,3S,4R,5R)-5-[2-chloro-6-(cyclopropylamino)purin-9-yl]-N-ethyl-3,4-dihydroxythiolane-2-carboxamide
CFAMM00399267 CHEMBL381868 Bioactive (2S,3S,4R,5R)-5-[2-chloro-6-(cyclopropylamino)purin-9-yl]-N-cyclopropyl-3,4-dihydroxythiolane-2-carboxamide
CFAMM00399253 CHEMBL611359 Bioactive (2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]thiolane-2-carboxamide
CFAMM00399266 CHEMBL596460 Bioactive (2S,3S,4R,5R)-N-cyclopropyl-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]thiolane-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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