CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10060
Family Name Wee1-like protein kinase and ALK tyrosine kinase receptor ligand CHEMBL1999485 family
No. of Seeds 1 No. of Other Members 9
Family Centroid CFAMM00399289 Functional Category Bioactive
Superfamily Sphingosine 1-phosphate receptor 1 and Wee1-like protein kinase Binder Superfamily
Class Class 3803

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
Nuclear factor NF-kappa-B p100 subunit Inhibitor GMX1777 Family 3 7
AP26113 family 16 90
Proto-oncogene tyrosine-protein kinase Src Inhibitor PD166285 ... 6 70
Platelet-derived growth factor receptor alpha and Fibroblast g... 3 47
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 3
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 0
Dihydrofolate reductase inhibitor AC1LA5HU family 8 4
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Inositol monophosphatase 1 inhibitor CHEMBL1588383 family 1 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0
Vascular endothelial growth factor receptor 2 ligand 1-[4-[6-a... 11 13
Vascular endothelial growth factor receptor 2 ligand urea deri... 2 1
Receptor tyrosine-protein kinase erbB-2 ligand N-[3-chloro-4-(... 4 3
ALK tyrosine kinase receptor ligand CHEMBL1946804 family 3 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 0
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Cyclin-dependent kinase 4 and Cyclin-dependent kinase 2 inhibi... 1 3
Vascular endothelial growth factor receptor 2 ligand pyrimidin... 2 2
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-071H3F fa... 3 0
Cyclin-dependent kinase 4 and Cyclin-dependent kinase 2 inhibi... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00399288 CHEMBL491773 Bioactive AGN-PC-072X7Y

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26371 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543