CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10067
Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand SureCN2346654 family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00254070 Functional Category Bioactive
Superfamily Histamine H4 receptor Ligand A-943931 Superfamily
Class Class 824

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mizolastine Family 14 603
Transient receptor potential cation channel subfamily V member... 15 457
C-C chemokine receptor type 5 Ligand Vicriviroc Family 4 31
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
GDC-0349 family 44 77
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 8 55
5-hydroxytryptamine receptor 2B Ligand MT-500 Family 8 39
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 32
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
D(2) dopamine receptor and D(3) dopamine receptor Ligand A-706... 4 20
Cyclin-dependent kinase 2 and Mitogen-activated protein kinase... 7 30
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2,6... 22 18
Cathepsin K Inhibitor 4-phenyl-6-propylpyrimidine-2-carbonitri... 6 10
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-amin... 4 11
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Histamine H4 receptor Ligand A-943931 Family 14 11
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 9
Cathepsin K and Potassium voltage-gated channel subfamily H me... 4 7
Cathepsin K and Potassium voltage-gated channel subfamily H me... 3 1
Cathepsin K and Potassium voltage-gated channel subfamily H me... 5 1
C-C chemokine receptor type 5 ligand AC1NUXE1 family 12 7
Histamine H4 receptor ligand 2-[[6-iodo-2-(4-methylpiperazin-1... 4 2
Survival motor neuron protein inhibitor CHEMBL1583999 family 1 3
Toll-like receptor 7 ligand 6-amino-2-(butylamino)-9-[[4-(dime... 5 4
Histamine H4 receptor ligand 4-[(3R)-3-(methylamino)pyrrolidin... 7 6
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 7 1
Translocator protein inhibitor N-butan-2-yl-4-(2-chlorophenyl)... 14 12
Substance-P receptor ligand Netupitant family 5 2
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[6-(3-methy... 2 5
G-protein coupled bile acid receptor 1 ligand 2-(ethylamino)-6... 5 4
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor (3R)-... 4 12
Histamine H4 receptor and Histamine H3 receptor ligand 7-cyclo... 2 0
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C9 inhib... 3 0
C-C chemokine receptor type 5 ligand N-[3-[4-[3-cyclohexyl-5-(... 5 4
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 7 2
C-C chemokine receptor type 5 ligand AC1MHPAK family 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27515 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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