CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10074
Family Name Serine/threonine-protein kinase Chk1 and Ribosomal protein S6 kinase alpha-3 inhibitor Kinome_2917 family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00127263 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 and Glycogen synthase kinase-3 beta Binder Superfamily
Class Class 2014

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
Serine/threonine-protein kinase Chk1 Inhibitor LY2603618 Family 2 1
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Serine/threonine-protein kinase Chk1 inhibitor Chk1_49 family 6 0
Serine/threonine-protein kinase Chk1 inhibitor AGN-PC-046QRM f... 1 2
Serine/threonine-protein kinase Chk1 inhibitor CHEMBL400574 fa... 26 4
Serine/threonine-protein kinase Chk1 inhibitor macrocyclic inh... 24 0
Serine/threonine-protein kinase Chk1 inhibitor CHEMBL398875 fa... 6 0
Serine/threonine-protein kinase Chk1 inhibitor macrocyclic inh... 5 0
Serine/threonine-protein kinase Chk1 inhibitor AGN-PC-076BW0 f... 2 0


External ID

Functional Category

Molecule Name

CFAMM00399357 CHEMBL219689 Bioactive macrocyclic inhibitor 21d
CFAMM00399355 CHEMBL219952 Bioactive macrocyclic inhibitor 21a
CFAMM00399354 CHEMBL219637 Bioactive macrocyclic inhibitor 24

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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