CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10086
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor SureCN13686709 family
No. of Seeds 5 No. of Other Members 3
Family Centroid CFAMM00399416 Functional Category Bioactive
Superfamily Protein farnesyltransferase subunit beta and Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Binder Superfamily 11
Class Class 2087

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 5 129
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Farnesyltransferase beta subunit, putative and Protein farnesy... 20 81
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-07RDWA fa... 1 4
Smoothened homolog inhibitor SureCN1091571 family 2 2
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Coagulation factor X inhibitor AGN-PC-0749BY family 5 9
Hepatocyte growth factor receptor ligand 5-[[6-(1-methylpyrazo... 4 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 3
Cholecystokinin receptor type A ligand 6-[2-[2-(cyclohexylmeth... 2 6
Growth hormone secretagogue receptor type 1 ligand SureCN36660... 4 14
P2X purinoceptor 7 inhibitor SureCN109432 family 10 28
P2X purinoceptor 7 inhibitor SureCN109149 family 8 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 1 0
Type-1 angiotensin II receptor ligand 2-[(2-ethyl-5,7-dimethyl... 5 3
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 2 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (3... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00399413 CHEMBL371010 Bioactive SureCN13686725
CFAMM00399419 CHEMBL200291 Bioactive N-[[4-[(4-cyanophenyl)methyl]-1,2,4-triazol-3-yl]methyl]-N-[(4-nitrophenyl)methyl]quinoline-2-carboxamide
CFAMM00399412 CHEMBL371423 Bioactive SureCN13686720
CFAMM00399418 CHEMBL371435 Bioactive SureCN13686724
CFAMM00399416 CHEMBL371484 Bioactive SureCN13686709

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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