CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1009
Family Name Transient receptor potential cation channel subfamily V member 1 ligand (E)-3-(4-hydroxy-3-methoxyphenyl)-1-thiomorpholin-4-ylprop-2-en-1-one family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00318421 Functional Category Bioactive with Natural Product
Superfamily Ferritin light chain and Retinal dehydrogenase 1 Binder Superfamily
Class Class 1466

Cousin Family NamesSeedsMembers
Zucapsacin family 7 177
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 6 40
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Intercellular adhesion molecule 1 Inhibitor Dehydropipernonali... 5 36
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 3 14
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 5 0
Beta-lactamase inhibitor CHEMBL1316873 family 1 1
Prelamin-A/C and Menin inhibitor CHEMBL1488543 family 1 0
Calpain-1 catalytic subunit inhibitor (2E)-2-[(3,4-dihydroxyph... 4 0
Adenosine receptor A2a and Adenosine receptor A2b ligand N-(2-... 3 0
Epidermal growth factor receptor ligand (3Z)-3-[[3-ethoxy-4-hy... 1 0
NP (e)-3-(3,4-dimethoxyphenyl)-1-((4as,8as)-4a-hydroxyoctahydr... 2 0


External ID

Functional Category

Molecule Name

CFAMM00318417 CHEMBL1097704 Bioactive (E)-3-(4-hydroxy-3-methoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one
CFAMM00318421 CHEMBL1096703 Bioactive (E)-3-(4-hydroxy-3-methoxyphenyl)-1-thiomorpholin-4-ylprop-2-en-1-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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