CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM101
Family Name Histamine H3 receptor and Histamine H2 receptor ligand N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]benzenesulfonamide family
No. of Seeds 16 No. of Other Members 5
Family Centroid CFAMM00307164 Functional Category Bioactive
Superfamily Histamine H3 receptor and Histamine H2 receptor Binder Superfamily
Class Class 3079

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand A-349821 Family 49 228
Histamine H3 receptor and Cytochrome P450 2D6 ligand ethyl 4-[... 5 5
Histamine H3 receptor ligand 2-(3,3-difluoropyrrolidin-1-yl)-1... 2 0
Histamine H3 receptor ligand SureCN7244264 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00307164 CHEMBL101691 Bioactive N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]benzenesulfonamide
CFAMM00307170 CHEMBL107162 Bioactive N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]-4-methoxybenzenesulfonamide
CFAMM00307163 CHEMBL2112451 Bioactive 4-cyano-N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]benzenesulfonamide
CFAMM00307156 CHEMBL103027 Bioactive N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]-3-methylbenzenesulfonamide
CFAMM00307169 CHEMBL321709 Bioactive 4-bromo-N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]benzenesulfonamide
CFAMM00307155 CHEMBL102925 Bioactive N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]-4-ethylbenzenesulfonamide
CFAMM00307168 CHEMBL102840 Bioactive N-[(3S)-1-[3-(4-acetylphenoxy)propyl]pyrrolidin-3-yl]-4-cyanobenzenesulfonamide
CFAMM00307161 CHEMBL107293 Bioactive N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]-4-methylbenzenesulfonamide
CFAMM00307175 CHEMBL104618 Bioactive N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]-2-fluorobenzenesulfonamide
CFAMM00307174 CHEMBL104809 Bioactive N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]-3-fluorobenzenesulfonamide
CFAMM00307166 CHEMBL104344 Bioactive 4-chloro-N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]benzenesulfonamide
CFAMM00307159 CHEMBL321320 Bioactive 3-chloro-N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]benzenesulfonamide
CFAMM00307173 CHEMBL101748 Bioactive 3-cyano-N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]benzenesulfonamide
CFAMM00307165 CHEMBL105071 Bioactive 4-tert-butyl-N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]benzenesulfonamide
CFAMM00307158 CHEMBL104808 Bioactive N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]-4-fluorobenzenesulfonamide
CFAMM00307171 CHEMBL102384 Bioactive 2-chloro-N-[(3S)-1-[3-[4-(cyclopropanecarbonyl)phenoxy]propyl]pyrrolidin-3-yl]benzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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