CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10105
Family Name BDNF/NT-3 growth factors receptor and NT-3 growth factor receptor ligand CHEMBL2007421 family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00399592 Functional Category Bioactive
Superfamily Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 Binder Superfamily 2
Class Class 3503

Cousin Family NamesSeedsMembers
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 15 12
cGMP-specific 3',5'-cyclic phosphodiesterase and Potassium vol... 13 4
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 9 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 3 2
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 6 0
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 3 0
High affinity nerve growth factor receptor ligand SureCN333709... 4 5
High affinity nerve growth factor receptor ligand SureCN334011... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00399589 CHEMBL515062 Bioactive SureCN589431
CFAMM00399588 CHEMBL513953 Bioactive SureCN589106
CFAMM00399585 CHEMBL457614 Bioactive 5-chloro-2-N-[(1S)-1-(5-fluoropyridin-2-yl)ethyl]-4-N-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42700 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543