CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10136
Family Name Cathepsin K inhibitor (1R,2R)-N-(cyanomethyl)-5,5-difluoro-2-[2-(4-methylsulfanylphenyl)phenyl]cyclohexane-1-carboxamide family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00399760 Functional Category Bioactive
Superfamily Cathepsin K Inhibitor Odanacatib Superfamily
Class Class 905

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Melatonin receptor type 1A Ligand N-(2,3-dihydro-1h-phenalen-2... 8 13
5-hydroxytryptamine receptor 6 ligand N-[[(1R)-6-(benzenesulfo... 8 2
Cathepsin K inhibitor (1R,2R)-N-(cyanomethyl)-2-[(4-methylsulf... 2 4
Cathepsin K inhibitor N-(cyanomethyl)-5,5-difluoro-2-[3-(4-met... 2 0
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 1
Cathepsin K inhibitor (1R,2R)-2-[(4-aminophenyl)sulfanylmethyl... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00399760 CHEMBL201782 Bioactive (1R,2R)-N-(cyanomethyl)-5,5-difluoro-2-[2-(4-methylsulfanylphenyl)phenyl]cyclohexane-1-carboxamide
CFAMM00399765 CHEMBL202103 Bioactive (1S,2S)-N-(cyanomethyl)-5,5-difluoro-2-[2-(4-methylsulfanylphenyl)phenyl]cyclohexane-1-carboxamide
CFAMM00399764 CHEMBL371954 Bioactive AGN-PC-00CWRS
CFAMM00399763 CHEMBL383612 Bioactive AGN-PC-046RTS
CFAMM00399762 CHEMBL201178 Bioactive (1R,2R)-N-(cyanomethyl)-2-[2-(4-methylsulfanylphenyl)phenyl]cyclohexane-1-carboxamide
CFAMM00399761 CHEMBL201914 Bioactive N-(cyanomethyl)-5,5-difluoro-2-[2-(4-methylsulfanylphenyl)phenyl]cyclohexane-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42570 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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