CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1014
Family Name 5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin transporter ligand SureCN6598110 family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00318463 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and Cholesteryl ester transfer protein Binder Superfamily
Class Class 490

Cousin Family NamesSeedsMembers
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 9 22
D(3) dopamine receptor and D(1A) dopamine receptor ligand N-[(... 6 14
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 4 8
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 1


External ID

Functional Category

Molecule Name

CFAMM00318462 CHEMBL337499 Bioactive 3-[4-(1,3-benzodioxol-4-yl)piperazin-1-yl]-1-(5-fluoro-1-benzothiophen-3-yl)propan-1-ol
CFAMM00318463 CHEMBL336842 Bioactive SureCN6598110
CFAMM00318454 CHEMBL1096903 Bioactive 3-[4-(1,3-benzodioxol-4-yl)-3-methylpiperazin-1-yl]-1-(5-fluoro-1-benzothiophen-3-yl)propan-1-ol
CFAMM00318460 CHEMBL337659 Bioactive SureCN6596685
CFAMM00318458 CHEMBL335082 Bioactive 1-(1-benzothiophen-3-yl)-3-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]propan-1-ol
CFAMM00318457 CHEMBL423896 Bioactive 3-[4-(3,4-dihydro-2H-1,5-benzodioxepin-6-yl)piperazin-1-yl]-1-(5-fluoro-1-benzothiophen-3-yl)propan-1-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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