CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10151
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4B and Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A inhibitor 5-(aminomethyl)-N-[(4-chlorophenyl)methyl]-2-[8-methoxy-2-(trifluoromethyl)quinolin-5-yl]-1,3-oxazole-4-carboxamide family
No. of Seeds 11 No. of Other Members 0
Family Centroid CFAMM00399893 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-specific 3',5'-cyclic phosphodiesterase 4B Inhibitor SCH-365351 Superfamily
Class Class 897

Cousin Family NamesSeedsMembers
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Benoxapr... 1 76
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Thyroid hormone receptor beta ligand CHEMBL1397256 family 1 12
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and Dual 3',5'... 27 20


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00399895 CHEMBL2012233 Bioactive 5-[(1S)-1-aminopropyl]-N-[(4-chlorophenyl)methyl]-2-[8-methoxy-2-(trifluoromethyl)quinolin-5-yl]-1,3-oxazole-4-carboxamide
CFAMM00399888 CHEMBL2012229 Bioactive 5-[(1S)-1-aminoethyl]-N-[(4-chloro-2-fluorophenyl)methyl]-2-[8-methoxy-2-(trifluoromethyl)quinolin-5-yl]-1,3-oxazole-4-carboxamide
CFAMM00399894 CHEMBL2012230 Bioactive 5-[(1S)-1-aminoethyl]-N-[(2,4-dichlorophenyl)methyl]-2-[8-methoxy-2-(trifluoromethyl)quinolin-5-yl]-1,3-oxazole-4-carboxamide
CFAMM00399893 CHEMBL2012209 Bioactive 5-(aminomethyl)-N-[(4-chlorophenyl)methyl]-2-[8-methoxy-2-(trifluoromethyl)quinolin-5-yl]-1,3-oxazole-4-carboxamide
CFAMM00399892 CHEMBL2012220 Bioactive 5-(aminomethyl)-N-[(4-chloro-2-fluorophenyl)methyl]-2-[8-methoxy-2-(trifluoromethyl)quinolin-5-yl]-1,3-oxazole-4-carboxamide
CFAMM00399898 CHEMBL2012218 Bioactive 5-(aminomethyl)-N-[(2-chloro-6-fluorophenyl)methyl]-2-[8-methoxy-2-(trifluoromethyl)quinolin-5-yl]-1,3-oxazole-4-carboxamide
CFAMM00399891 CHEMBL2012221 Bioactive 5-(aminomethyl)-N-[(2,4-dichlorophenyl)methyl]-2-[8-methoxy-2-(trifluoromethyl)quinolin-5-yl]-1,3-oxazole-4-carboxamide
CFAMM00399897 CHEMBL2012215 Bioactive 5-(aminomethyl)-N-[(2-chlorophenyl)methyl]-2-[8-methoxy-2-(trifluoromethyl)quinolin-5-yl]-1,3-oxazole-4-carboxamide
CFAMM00399890 CHEMBL2012223 Bioactive 5-[(1S)-1-aminoethyl]-N-[(4-chlorophenyl)methyl]-2-[8-methoxy-2-(trifluoromethyl)quinolin-5-yl]-1,3-oxazole-4-carboxamide
CFAMM00399896 CHEMBL2012213 Bioactive 5-(aminomethyl)-N-[(3-chlorophenyl)methyl]-2-[8-methoxy-2-(trifluoromethyl)quinolin-5-yl]-1,3-oxazole-4-carboxamide
CFAMM00399889 CHEMBL2012227 Bioactive 5-[(1S)-1-aminoethyl]-N-[(2-chloro-6-fluorophenyl)methyl]-2-[8-methoxy-2-(trifluoromethyl)quinolin-5-yl]-1,3-oxazole-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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