CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10153
Family Name Proteinase-activated receptor 1 ligand (3R,3aR,4S,5R,6S,7aS)-5-ethyl-7a-hydroxy-4-[(E)-2-[5-(2-methoxyphenyl)pyridin-2-yl]ethenyl]-3,6-dimethyl-3,3a,4,5,6,7-hexahydro-2-benzofuran-1-one family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00399910 Functional Category Bioactive
Superfamily Integrin beta-3 and Integrin alpha-IIb Binder Superfamily 10
Class Class 2015

Cousin Family NamesSeedsMembers
Proteinase-activated receptor 1 Ligand SCH-530348 Family 20 215
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
RAF proto-oncogene serine/threonine-protein kinase Inhibitor 5... 3 7
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 4 5
Renin Inhibitor CP-305202 Family 9 30
Acetylcholinesterase Inhibitor Lysicamine Family 2 8
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Leukotriene B4 receptor 1 ligand AGN-PC-04XM3V family 3 10
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
Prostaglandin D2 receptor 2 ligand SureCN137822 family 3 0
Endothelin-1 receptor ligand SureCN8118632 family 4 5
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 5 12
Retinoic acid receptor RXR-alpha ligand 6-[(3-butoxy-5,5,8,8-t... 2 2
Proteinase-activated receptor 1 ligand (3R,3aR,4S,5R,6S,7aS)-5... 1 2
Peroxisome proliferator-activated receptor delta and Peroxisom... 1 1
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 2
Thromboxane-A synthase inhibitor (E)-7-[4-[5-[(2S,4S,5R)-5-[(Z... 3 9
Proteinase-activated receptor 1 ligand (3R,3aS,4S,4aR,8aS,9aR)... 1 11
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
Proteinase-activated receptor 1 ligand ethyl N-[(1R,3aR,4aR,6R... 1 4
Bile acid receptor ligand pyridin-4-yl (1R,3aS,5aR,5bR,7aR,9S,... 1 0
Retinoic acid receptor RXR-alpha and Retinoic acid receptor RX... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00399912 CHEMBL2012510 Bioactive (3R,3aR,4S,5R,6S,7aS)-5-ethyl-4-[(E)-2-[5-(furan-3-yl)pyridin-2-yl]ethenyl]-7a-hydroxy-3,6-dimethyl-3,3a,4,5,6,7-hexahydro-2-benzofuran-1-one
CFAMM00399910 CHEMBL2012505 Bioactive (3R,3aR,4S,5R,6S,7aS)-5-ethyl-7a-hydroxy-4-[(E)-2-[5-(2-methoxyphenyl)pyridin-2-yl]ethenyl]-3,6-dimethyl-3,3a,4,5,6,7-hexahydro-2-benzofuran-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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