CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10155
Family Name Beta-3 adrenergic receptor ligand 6-[4-[2-[[(2S)-3-[(3,3-dimethyl-2-oxo-1H-indol-4-yl)oxy]-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]pyridine-3-carboxamide family
No. of Seeds 6 No. of Other Members 7
Family Centroid CFAMM00399924 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Pol polyprotein Binder Superfamily
Class Class 630

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 7 11
Pol polyprotein inhibitor AC1LARNY family 28 17
Pol polyprotein inhibitor (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5... 12 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 36 18
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
Pol polyprotein and Cytochrome P450 3A4 inhibitor P3 arylpyrro... 19 1
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 2
Pol polyprotein inhibitor ethyl)-amide family 4 0
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 14 2
Pol polyprotein inhibitor pyridylfuran analog 14 family 6 0
Beta-3 adrenergic receptor ligand 6-[4-[2-[[(2S)-3-[(3-ethyl-2... 5 3
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... 1 4
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 3
Tyrosine-protein kinase JAK3 and Activated CDC42 kinase 1 inhi... 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00399927 CHEMBL2012521 Bioactive 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]pyridine-3-carboxamide;hydrochloride
CFAMM00399920 CHEMBL2012522 Bioactive butanedioic acid;6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]pyridine-3-carboxamide
CFAMM00399924 CHEMBL251372 Bioactive 6-[4-[2-[[(2S)-3-[(3,3-dimethyl-2-oxo-1H-indol-4-yl)oxy]-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]pyridine-3-carboxamide
CFAMM00399917 CHEMBL248547 Bioactive 6-[4-[2-[[(2S)-2-hydroxy-3-(2-oxospiro[1H-indole-3,1'-cyclopropane]-4-yl)oxypropyl]amino]-2-methylpropyl]phenoxy]pyridine-3-carboxamide
CFAMM00399916 CHEMBL251579 Bioactive 6-[4-[2-[[(2S)-3-[(3,3-diethyl-2-oxo-1H-indol-4-yl)oxy]-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]pyridine-3-carboxamide
CFAMM00399922 CHEMBL248751 Bioactive 6-[4-[2-[[(2S)-2-hydroxy-3-(2-oxospiro[1H-indole-3,1'-cyclohexane]-4-yl)oxypropyl]amino]-2-methylpropyl]phenoxy]pyridine-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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