CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10159
Family Name Kappa-type opioid receptor and Cytochrome P450 2D6 ligand SureCN5342053 family
No. of Seeds 11 No. of Other Members 9
Family Centroid CFAMM00399960 Functional Category Bioactive with Natural Product
Superfamily 5-hydroxytryptamine receptor 4 Ligand TD-5108 Superfamily
Class Class 1656

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Kappa-type opioid receptor Ligand Asimadoline Family 14 54
Pan-DAC Inhibitor AR-42 Family 21 153
Nociceptin receptor Ligand J-113397 Family 3 14
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
5-hydroxytryptamine receptor 4 Ligand TD-5108 Family 21 24
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Sphingosine kinase 2 Inhibitor (r)-2-amino-3-(4-octylphenylami... 1 16
Sphingosine kinase 2 Inhibitor (r)-2-amino-4-hydroxy-n-(4-octy... 3 9
Disintegrin and metalloproteinase domain-containing protein 17... 2 2
Pol polyprotein inhibitor AC1LAMTL family 11 15
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
Melanin-concentrating hormone receptor 1 ligand 1-[4-(3-cyanop... 4 9
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Kappa-type opioid receptor ligand SureCN5346063 family 4 0
C-C chemokine receptor type 2 ligand N-[2-[[(2S,3S)-1-[(2,4-di... 13 8
C-C chemokine receptor type 2 ligand N-[3-amino-5-(trifluorome... 4 1
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-cyc... 2 1
Pol polyprotein inhibitor DMP-450 family 9 4
Beta-secretase 1 and Cathepsin D inhibitor (4S)-N-[(2S,3R)-4-[... 3 0
Kappa-type opioid receptor ligand 1-[4-acetyl-2-[[(3S)-3-hydro... 1 0
Neuropeptide Y receptor type 5 ligand 3-(4-benzylphenyl)-1-[(1... 2 4
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 2
Dipeptidyl peptidase 4 inhibitor 4-[[(3S,5S)-5-[(2S)-2-cyanopy... 4 12
Sodium-dependent noradrenaline transporter inhibitor SureCN408... 5 12
Dipeptidyl peptidase 4 inhibitor (2S,4S)-1-[2-[[1-[4-cyano-2-(... 2 0
5-hydroxytryptamine receptor 4 ligand 2-oxo-N-[(1R,5S)-8-(2-pi... 13 5
Sodium-dependent noradrenaline transporter and Sodium-dependen... 12 16
Kappa-type opioid receptor and Delta-type opioid receptor liga... 3 1
Sphingosine 1-phosphate receptor 5 and Sphingosine 1-phosphate... 1 0
Muscarinic acetylcholine receptor M4 and Potassium voltage-gat... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00399974 CHEMBL382449 Bioactive SureCN5347865
CFAMM00399960 CHEMBL201884 Bioactive SureCN5342053
CFAMM00399973 CHEMBL397474 Bioactive SureCN5347989
CFAMM00399971 CHEMBL435132 Bioactive SureCN5342376
CFAMM00399969 CHEMBL230288 Bioactive SureCN5348426
CFAMM00399975 CHEMBL203306 Bioactive SureCN5342381
CFAMM00399968 CHEMBL230502 Bioactive 2-[[[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-methylcarbamoyl]amino]-N-phenylacetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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