CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1017
Family Name Integrin beta-3 and Integrin alpha-V inhibitor SureCN547914 family
No. of Seeds 8 No. of Other Members 32
Family Centroid CFAMM00318499 Functional Category Bioactive with Natural Product
Superfamily Prostaglandin D2 receptor and Integrin beta-3 Binder Superfamily
Class Class 328

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Peptide deformylase, mitochondrial inhibitor folic acid analog... 59 98
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Mitogen-activated protein kinase 12 Inhibitor VX-702 Family 3 49
Thromboxane A2 receptor Ligand Bibv 308 Family 14 40
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Integrin beta-3 Inhibitor Elarofiban Family 28 45
Integrin alpha-V and Integrin beta-3 Inhibitor SB-223245 Family 27 36
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
D(2) dopamine receptor and D(3) dopamine receptor Ligand A-706... 4 20
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(6-methylpy... 4 3
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Metabotropic glutamate receptor 5 Ligand 3-cyano-5-fluoro-n-(p... 2 9
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 6-(4-... 3 6
Integrin alpha-V and Integrin beta-5 inhibitor SureCN6563167 f... 2 10
Integrin beta-3 and Integrin alpha-V inhibitor SureCN3888804 f... 11 13
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-quinolin... 6 8
Caspase-1 inhibitor (3S)-3-[[(2S)-4-[2-(1,2-dimethylindol-3-yl... 3 4
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[[4-[2-(... 3 3
5-hydroxytryptamine receptor 1A ligand AGN-PC-03ZB72 family 10 8
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[6-m... 13 12
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6359092 f... 9 5
Corticotropin-releasing factor receptor 1 ligand Pyridopyrazin... 3 5
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-2-[[(1R,4S... 3 0
B1 bradykinin receptor ligand AGN-PC-005XAO family 3 17
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-2-(benzene... 3 2
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[5-methy... 4 5
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 18 5
5-hydroxytryptamine receptor 3A ligand 3-methyl-N-[7-[[3-methy... 2 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN2833591 f... 4 6
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(2,6-di... 6 5
Integrin beta-3 and Integrin alpha-V inhibitor SureCN2842307 f... 4 0
Substance-P receptor ligand Netupitant family 5 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 6-(di... 4 8
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-00IW9E f... 3 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor 6-... 1 0
G-protein coupled bile acid receptor 1 ligand 2-(ethylamino)-6... 5 4
Integrin alpha-V and Integrin beta-6 inhibitor 3-[[2-[4-[(4-me... 4 3
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(3-fluor... 10 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3S)-3-[[3-(2... 4 2
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-074ASZ f... 5 0
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[4-(... 3 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3S)-3-[[2-[(... 3 1
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1
Cannabinoid receptor 2 ligand AGN-PC-00SRU5 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00318488 CHEMBL185496 Bioactive SureCN6421488
CFAMM00318507 CHEMBL183998 Bioactive (E)-3-(3-fluorophenyl)-9-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)non-4-enoic acid
CFAMM00318479 CHEMBL186699 Bioactive (3S)-3-[1-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanoyl]piperidin-4-yl]-3-(1,2,3,4-tetrahydroquinolin-3-yl)propanoic acid
CFAMM00318493 CHEMBL109703 Bioactive AGN-PC-03RSAX
CFAMM00318499 CHEMBL368693 Bioactive SureCN547914
CFAMM00318477 CHEMBL185666 Bioactive SureCN547592
CFAMM00318491 CHEMBL365272 Bioactive SureCN548056
CFAMM00318475 CHEMBL188406 Bioactive SureCN6420759

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46027 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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