CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10179
Family Name 5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine receptor 3B ligand AGN-PC-002GOC family
No. of Seeds 11 No. of Other Members 3
Family Centroid CFAMM00400136 Functional Category Bioactive
Superfamily Cannabinoid receptor 2 and 5-hydroxytryptamine receptor 3B Binder Superfamily
Class Class 673

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Dopamine receptor Ligand Domperidone Family 2 21
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Nociceptin receptor Ligand J-113397 Family 3 14
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 5 65
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Induced myeloid leukemia cell differentiation protein Mcl-1 an... 2 7
Reverse transcriptase Inhibitor Tibo Family 2 8
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 3 3
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 5 2
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 5 5
B2 bradykinin receptor ligand AGN-PC-074WA4 family 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 6 12
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 1
Cannabinoid receptor 2 ligand SureCN738026 family 5 68
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 3 1
Survival motor neuron protein and 15-hydroxyprostaglandin dehy... 1 4
Substance-P receptor ligand (2S,4S)-2-N-[3-(diethylamino)propy... 2 7
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
Cathepsin K and Cathepsin L1 inhibitor 1-[(2S)-1-[[cyano(methy... 2 1
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S)-4-anilinopyrr... 2 13
D(2) dopamine receptor and Potassium voltage-gated channel sub... 1 1
Nociceptin receptor ligand 2-[3-[1-[(1R)-1,2-dihydroacenaphthy... 2 0
5-hydroxytryptamine receptor 4 ligand 6-fluoro-N-[[1-[(4-hydro... 1 1
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 3 1
Histamine H3 receptor and Histamine receptor H3 ligand N-[4-[3... 5 1
Histamine H3 receptor and Histamine receptor H3 ligand 1-cyclo... 3 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 3 5
Cannabinoid receptor 2 ligand SureCN738244 family 1 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 2 4
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 0
Gastrin/cholecystokinin type B receptor ligand 2-[5-cyclohexyl... 2 1
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00400127 CHEMBL95661 Bioactive AGN-PC-00EX0V
CFAMM00400133 CHEMBL540017 Bioactive AGN-PC-07C1Q5
CFAMM00400126 CHEMBL97019 Bioactive 3-cyclopropyl-2-oxo-N-[2-(4-propan-2-ylpiperazin-1-yl)ethyl]benzimidazole-1-carboxamide
CFAMM00400132 CHEMBL293468 Bioactive 127618-28-4
CFAMM00400131 CHEMBL64986 Bioactive SureCN7419814
CFAMM00400130 CHEMBL63742 Bioactive AGN-PC-002GOD
CFAMM00400136 CHEMBL293239 Bioactive AGN-PC-002GOC
CFAMM00400135 CHEMBL544755 Bioactive Bimu 1

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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