CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10188
Family Name Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(1,3-benzodioxol-5-yl)-4-[3-[4-[(4-methylpyridin-2-yl)amino]butyl]-1,2,4-oxadiazol-5-yl]butanoic acid family
No. of Seeds 8 No. of Other Members 3
Family Centroid CFAMM00400261 Functional Category Bioactive
Superfamily Plasminogen and Integrin beta-3 Binder Superfamily
Class Class 513

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Integrin beta-3 and Integrin alpha-V inhibitor methyl (3S)-3-(... 12 13
Endothelin-1 receptor and Endothelin B receptor ligand (5S,6R,... 23 8
Endothelin-1 receptor and Endothelin B receptor ligand SureCN1... 3 16
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(4-ethox... 4 5
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(1,3-ben... 6 5
Integrin beta-3 and Integrin alpha-V inhibitor 2-(2,3-dihydro-... 13 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor Sure... 14 8
Integrin beta-3 and Integrin alpha-V inhibitor (3S,7S)-7-hydro... 5 1
Integrin beta-3 and Integrin alpha-V inhibitor SureCN2924568 f... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN8335217 f... 2 1
Integrin beta-3 and Integrin alpha-V inhibitor SureCN2842043 f... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN2836956 f... 3 0
Nitric oxide synthase, inducible inhibitor SureCN5194847 family 24 48
Nitric oxide synthase, inducible inhibitor N-(1,3-benzodioxol-... 11 1
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-03OERH f... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00400263 CHEMBL202081 Bioactive (3S)-3-(1,3-benzodioxol-5-yl)-4-[3-[4-[(4-morpholin-4-ylpyridin-2-yl)amino]butyl]-1,2,4-oxadiazol-5-yl]butanoic acid
CFAMM00400256 CHEMBL201568 Bioactive (3S)-3-(1,3-benzodioxol-5-yl)-4-[3-[4-(pyridin-2-ylamino)butyl]-1,2,4-oxadiazol-5-yl]butanoic acid
CFAMM00400255 CHEMBL379444 Bioactive SureCN2831928
CFAMM00400261 CHEMBL202342 Bioactive (3S)-3-(1,3-benzodioxol-5-yl)-4-[3-[4-[(4-methylpyridin-2-yl)amino]butyl]-1,2,4-oxadiazol-5-yl]butanoic acid
CFAMM00400260 CHEMBL434191 Bioactive (3S)-3-(1,3-benzodioxol-5-yl)-4-[3-[4-[(4-thiomorpholin-4-ylpyridin-2-yl)amino]butyl]-1,2,4-oxadiazol-5-yl]butanoic acid
CFAMM00400257 CHEMBL383366 Bioactive (3S)-3-(1,3-benzodioxol-5-yl)-4-[3-[4-[(4-methoxypyridin-2-yl)amino]butyl]-1,2,4-oxadiazol-5-yl]butanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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