CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1019
Family Name Histamine H3 receptor ligand SureCN4319687 family
No. of Seeds 8 No. of Other Members 15
Family Centroid CFAMM00317947 Functional Category Bioactive
Superfamily Histamine H3 receptor and Dipeptidyl peptidase 4 Binder Superfamily
Class Class 412

Cousin Family NamesSeedsMembers
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Irdabisant family 49 53
Plitidepsin family 15 5
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Oxytocin receptor Ligand [mpa1, D-tyr(et)2, D-tic7]ot Family 43 26
Histamine H3 receptor ligand SureCN4316818 family 11 24
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 4
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 2
Growth hormone secretagogue receptor type 1 ligand 2-amino-2-m... 1 0
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6S... 1 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 12
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 4
Dipeptidyl peptidase 4 inhibitor 2-cyanopyrrolidine 21e family 6 7
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 7 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 3
Pol polyprotein inhibitor N-[2-Hydroxy-2-(8-Isopropyl-6,9-Diox... 7 6
Pol polyprotein inhibitor (3S)-N-tert-butyl-2-[(2R)-2-[(3S,6S,... 3 1
Kappa-type opioid receptor ligand N-methyl-N-[(2S)-3-methyl-1-... 1 4
Caspase-1 inhibitor 3-[[(2S)-4-hydroxy-1-[(2S)-3-methyl-2-[[(E... 1 0


External ID

Functional Category

Molecule Name

CFAMM00318527 CHEMBL1823046 Bioactive AGN-PC-07ZEUY
CFAMM00318533 CHEMBL1098883 Bioactive SureCN4315543
CFAMM00318526 CHEMBL1823047 Bioactive AGN-PC-07ZEUZ
CFAMM00318525 CHEMBL1097883 Bioactive SureCN4317851
CFAMM00318518 CHEMBL1097143 Bioactive SureCN4318197
CFAMM00318530 CHEMBL1098884 Bioactive SureCN4315539
CFAMM00318523 CHEMBL1099146 Bioactive SureCN4325638

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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