CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10197
Family Name Neuropeptide Y receptor type 5 ligand AGN-PC-07R6YQ family
No. of Seeds 7 No. of Other Members 7
Family Centroid CFAMM00400333 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 and Caspase-7 Binder Superfamily
Class Class 4316

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Smoothened homolog Inhibitor LDE225 Family 3 76
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 7 3
Platelet-activating factor receptor ligand SureCN7491834 family 28 15
B1 bradykinin receptor ligand AGN-PC-005XAO family 3 17
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Mitogen-activated protein kinase 14 inhibitor methyl 4-[5-(eth... 3 11
Neuropeptide Y receptor type 5 ligand 3-[1-(2-fluorophenyl)pyr... 5 4
Neuropeptide Y receptor type 5 ligand SureCN4170426 family 4 13
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 3-methyl-4... 15 14
B1 bradykinin receptor ligand methyl 2-fluoro-6-[3-fluoro-4-[[... 22 11
Lysine--tRNA ligase inhibitor 4-[[2-(2-piperazin-1-ylpyridin-4... 2 0
B1 bradykinin receptor ligand methyl 2-[4-[(1R)-1-[[3-[(2-cyan... 8 7
Smoothened homolog inhibitor N-[4-methyl-3-(5-phenyl-1H-imidaz... 1 0
Melanocortin receptor 4 ligand AGN-PC-076AMT family 2 9
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
Histamine H3 receptor ligand AGN-PC-075YVW family 1 2
Integrin beta-1 and Integrin alpha-5 inhibitor SureCN14453385 ... 5 0
Cell division cycle 7-related protein kinase inhibitor Pyrrolo... 2 6
Neuropeptide Y receptor type 5 ligand AGN-PC-02WBQH family 7 1
Neuropeptide Y receptor type 5 ligand AGN-PC-077LX1 family 8 1
Neuropeptide Y receptor type 5 ligand SureCN5430956 family 11 1
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Neuropeptide Y receptor type 5 ligand AGN-PC-07CRFU family 18 0
Neuropeptide Y receptor type 5 ligand SureCN917790 family 9 0
Neuropeptide Y receptor type 5 ligand SureCN916457 family 2 2
Serine/threonine-protein kinase mTOR inhibitor 3-(cyclohexylme... 2 1
Corticotropin-releasing factor receptor 1 ligand AGN-PC-006EKH... 1 0


External ID

Functional Category

Molecule Name

CFAMM00400332 CHEMBL593466 Bioactive AGN-PC-00AJUO
CFAMM00400331 CHEMBL593934 Bioactive SureCN4168587
CFAMM00400329 CHEMBL595121 Bioactive AGN-PC-07R6ZP
CFAMM00400328 CHEMBL596031 Bioactive SureCN916485
CFAMM00400334 CHEMBL2016739 Bioactive 1-methyl-1-(1'-oxospiro[cyclohexane-4,3'-furo[3,4-c]pyridine]-1-yl)-3-(5-phenylpyrazin-2-yl)urea
CFAMM00400339 CHEMBL491930 Bioactive SureCN918154
CFAMM00400333 CHEMBL607144 Bioactive AGN-PC-07R6YQ

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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