Cousin Family Names | Seeds | Members |
---|
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... | 4 | 301 |
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... | 5 | 644 |
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... | 6 | 537 |
Reverse transcriptase Inhibitor Delavirdine Family | 1 | 68 |
Reverse transcriptase Inhibitor Nevirapine Family | 23 | 640 |
5-hydroxytryptamine receptor Ligand Ramosetron Family | 10 | 219 |
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family | 32 | 639 |
Tubulin beta chain Inhibitor Mebendazole Family | 12 | 84 |
Peptide deformylase, mitochondrial inhibitor folic acid analog... | 59 | 98 |
Histamine H1 receptor Ligand Mizolastine Family | 14 | 603 |
Prothrombin Inhibitor Dabigatran Family | 7 | 182 |
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family | 15 | 444 |
C-X-C chemokine receptor type 4 Ligand AMD-070 Family | 12 | 800 |
Purine nucleoside phosphorylase Inhibitor BCX-34 Family | 2 | 31 |
Transient receptor potential cation channel subfamily V member... | 15 | 457 |
Transient receptor potential cation channel subfamily V member... | 6 | 66 |
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... | 25 | 124 |
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family | 13 | 155 |
Cannabinoid receptor 1 Ligand CP-945598 Family | 18 | 173 |
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family | 10 | 81 |
Mast/stem cell growth factor receptor Kit and Vascular endothe... | 4 | 47 |
Translocator protein Inhibitor Emapunil Family | 7 | 89 |
Growth hormone receptor Ligand EP-51216 Family | 34 | 390 |
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... | 14 | 234 |
Protein kinase C alpha type and Protein kinase C beta type Inh... | 16 | 86 |
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family | 53 | 580 |
Dipeptidyl peptidase 4 Inhibitor SSR-162369 Family | 8 | 27 |
NS5A protein Inhibitor Bms 790052 Family | 5 | 9 |
BIBT986 family | 7 | 96 |
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... | 35 | 69 |
IPI-145 family | 2 | 4 |
SB989 family | 17 | 91 |
GDC-0349 family | 44 | 77 |
Histone deacetylase Inhibitor JNJ-26481585 Family | 2 | 5 |
Histone deacetylase 6 Inhibitor ACY-1215 Family | 10 | 230 |
PHA848125 family | 13 | 138 |
CC-486 family | 7 | 103 |
JAK Inhibitor Momelotinib Family | 33 | 83 |
Eluxadoline family | 4 | 85 |
Vascular endothelial growth factor receptor 2 Ligand XL999 Family | 11 | 87 |
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family | 7 | 44 |
XL-888 family | 16 | 85 |
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... | 12 | 213 |
Platelet activating factor, putative Inhibitor ABT-491 Family | 22 | 62 |
Kappa-type opioid receptor Ligand Brl 52974 Family | 2 | 27 |
Bacterial outer membrane Inhibitor HKI-9924129 Family | 19 | 85 |
Class II cytokine receptor Ligand IL-10 Family | 7 | 45 |
D(4) dopamine receptor Ligand L-745,870 Family | 30 | 205 |
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Olprin... | 2 | 7 |
Cyclin-dependent kinase 4 and Cyclin-dependent kinase 6 Inhibi... | 2 | 3 |
Histamine H3 receptor Ligand SCH79687 Family | 11 | 29 |
Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... | 10 | 43 |
Vascular endothelial growth factor receptor 2 Ligand 6-(1h-ben... | 2 | 5 |
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... | 18 | 109 |
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... | 7 | 117 |
Integrin alpha-V and Integrin beta-3 Inhibitor SB-223245 Family | 27 | 36 |
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family | 47 | 54 |
Epidermal growth factor receptor Ligand PD-158780 Family | 98 | 89 |
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... | 7 | 102 |
Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... | 2 | 5 |
Cyclin-dependent kinase 4 Inhibitor 1-(9-oxo-9h-fluoren-4-yl)-... | 3 | 5 |
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... | 6 | 5 |
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... | 19 | 165 |
Telomerase reverse transcriptase Inhibitor HOE-33258 Family | 10 | 33 |
Alpha-1A adrenergic receptor Ligand A-315456 Family | 7 | 17 |
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... | 19 | 103 |
RAC-gamma serine/threonine-protein kinase and Rho-associated p... | 16 | 46 |
D(2) dopamine receptor and D(3) dopamine receptor Ligand A-706... | 4 | 20 |
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family | 112 | 67 |
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... | 28 | 47 |
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... | 38 | 60 |
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... | 20 | 18 |
Nitric oxide synthase, inducible and Nitric oxide synthase, br... | 4 | 6 |
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... | 2 | 3 |
Fatty-acid amide hydrolase 1 Inhibitor JNJ-1661010 Family | 3 | 14 |
Aromatase and Cytochrome P450 26A1 Inhibitor Liarozole Family | 4 | 1 |
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... | 219 | 124 |
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... | 4 | 31 |
Calcitonin gene-related peptide type 1 receptor Ligand Isomer ... | 30 | 31 |
Serine/threonine-protein kinase mTOR Inhibitor 4-(2-(1h-indol-... | 2 | 15 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 24 | 79 |
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand N-(9h-... | 5 | 2 |
Type-2 angiotensin II receptor Ligand L-158282 Family | 24 | 58 |
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... | 2 | 11 |
Sodium channel protein type 1 subunit alpha and Sodium channel... | 10 | 14 |
Glutamate receptor 1 Ligand Piriqualone Family | 8 | 67 |
Herpes simplex virus type 1 thymidine kinase Inhibitor N2-(3-t... | 1 | 2 |
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... | 13 | 15 |
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... | 12 | 160 |
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... | 10 | 14 |
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... | 20 | 90 |
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... | 42 | 7 |
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... | 7 | 77 |
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... | 1 | 2 |
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... | 4 | 15 |
Prothrombin inhibitor SureCN5855286 family | 15 | 8 |
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... | 8 | 12 |
Prothrombin inhibitor SureCN5854779 family | 4 | 9 |
Prothrombin inhibitor SureCN5856722 family | 3 | 16 |
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... | 2 | 13 |
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... | 1 | 8 |
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... | 1 | 4 |
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... | 8 | 7 |
Orexin receptor type 2 and Orexin receptor type 1 ligand [(7R)... | 10 | 10 |
Acetylcholinesterase inhibitor SureCN251059 family | 2 | 16 |
Orexin receptor type 2 and Orexin receptor type 1 ligand SureC... | 2 | 3 |
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... | 5 | 10 |
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA4D family | 1 | 0 |
Bombesin receptor subtype-3 ligand SureCN3515839 family | 1 | 0 |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... | 4 | 2 |
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... | 10 | 3 |
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... | 2 | 12 |
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-07ZE3... | 6 | 1 |
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-07RDWA fa... | 1 | 4 |
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... | 7 | 7 |
Integrin beta-3 and Integrin alpha-V inhibitor SureCN3888804 f... | 11 | 13 |
Platelet-activating factor receptor ligand SureCN9384429 family | 11 | 3 |
RAC-alpha serine/threonine-protein kinase inhibitor SureCN4728... | 11 | 6 |
Macrophage colony-stimulating factor 1 receptor ligand SureCN1... | 28 | 9 |
Macrophage colony-stimulating factor 1 receptor and Cytochrome... | 13 | 3 |
Platelet-activating factor receptor ligand 8-bromo-2-[4-(2-met... | 2 | 2 |
Platelet-activating factor receptor ligand 5-methyl-2-[4-(2-me... | 1 | 2 |
Histamine H4 receptor ligand SureCN602132 family | 1 | 8 |
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... | 1 | 2 |
Smoothened homolog inhibitor SureCN1091571 family | 2 | 2 |
Transient receptor potential cation channel subfamily V member... | 1 | 4 |
Serine/threonine-protein kinase D1 inhibitor SureCN1424142 family | 13 | 8 |
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor Su... | 16 | 5 |
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... | 3 | 7 |
Cannabinoid receptor 2 ligand AGN-PC-080WIY family | 1 | 0 |
Histamine H3 receptor ligand 1-[1-[1-[(2-aminopyridin-4-yl)met... | 16 | 9 |
Cathepsin K and Potassium voltage-gated channel subfamily H me... | 4 | 7 |
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... | 7 | 10 |
TGF-beta receptor type-1 ligand 6-[4-ethyl-2-(6-methylpyridin-... | 9 | 11 |
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... | 4 | 10 |
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... | 2 | 4 |
Serine/threonine-protein kinase mTOR and RAC-alpha serine/thre... | 3 | 3 |
RAC-alpha serine/threonine-protein kinase and Proline-rich AKT... | 2 | 4 |
RAC-alpha serine/threonine-protein kinase inhibitor (2S)-3-ami... | 2 | 0 |
Adenosine receptor A2a ligand SureCN14156209 family | 3 | 2 |
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-09M4U... | 4 | 5 |
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-09M45... | 8 | 1 |
Cell division cycle 7-related protein kinase and Cyclin-depend... | 2 | 9 |
Cell division cycle 7-related protein kinase inhibitor pyrrolo... | 4 | 10 |
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... | 5 | 8 |
5-hydroxytryptamine receptor 1A ligand AGN-PC-03ZB72 family | 10 | 8 |
Tyrosine-protein kinase JAK2 and Potassium voltage-gated chann... | 2 | 7 |
Gonadotropin-releasing hormone receptor ligand AGN-PC-075KV1 f... | 4 | 1 |
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... | 3 | 6 |
Mitogen-activated protein kinase 1 and Cytochrome P450 3A4 inh... | 1 | 0 |
C-C chemokine receptor type 5 ligand SureCN1573831 family | 4 | 3 |
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... | 7 | 29 |
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... | 3 | 3 |
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... | 8 | 4 |
G1/S-specific cyclin-D1 and G1/S-specific cyclin-D3 inhibitor ... | 6 | 3 |
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... | 3 | 1 |
Prelamin-A/C and Lethal(3)malignant brain tumor-like protein 1... | 1 | 1 |
5-hydroxytryptamine receptor 4 ligand 6-chloro-N-[[1-(2-methyl... | 10 | 19 |
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... | 4 | 2 |
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... | 6 | 2 |
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... | 1 | 0 |
Cellular tumor antigen p53 and Microtubule-associated protein ... | 1 | 1 |
Renin and Cathepsin D inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-... | 2 | 2 |
Nuclear receptor ROR-gamma and Mitogen-activated protein kinas... | 1 | 10 |
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... | 4 | 4 |
Prelamin-A/C and Cellular tumor antigen p53 inhibitor CHEMBL16... | 1 | 7 |
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... | 2 | 0 |
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... | 1 | 1 |
RAC-alpha serine/threonine-protein kinase inhibitor 2-[(4-chlo... | 11 | 2 |
RAC-alpha serine/threonine-protein kinase inhibitor 2-[(3,4-di... | 3 | 1 |
Prothrombin and Trypsin-1 inhibitor 2-[6-methyl-2-oxo-3-(2-pyr... | 4 | 2 |
C-C chemokine receptor type 5 and Potassium voltage-gated chan... | 21 | 32 |
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... | 9 | 3 |
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... | 9 | 10 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 3 | 1 |
Insulin-like growth factor 1 receptor ligand AGN-PC-09QGLU family | 3 | 1 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 2 | 2 |
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... | 4 | 14 |
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family | 8 | 15 |
Lysosomal Pro-X carboxypeptidase inhibitor N-[(1S)-1-(5,6-dich... | 3 | 21 |
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... | 2 | 2 |
Toll-like receptor 7 ligand 6-amino-2-(butylamino)-9-[[4-(dime... | 5 | 4 |
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... | 1 | 1 |
Cannabinoid receptor 2 ligand AGN-PC-0A9SMV family | 1 | 1 |
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... | 4 | 7 |
Signal transducer and activator of transcription 6 inhibitor A... | 3 | 0 |
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... | 3 | 0 |
Tyrosine-protein kinase ITK/TSK and Receptor-type tyrosine-pro... | 1 | 0 |
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... | 14 | 0 |
C-C chemokine receptor type 5 ligand methyl N-cyano-4-[2-[(1R,... | 8 | 8 |
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... | 15 | 7 |
Corticotropin-releasing factor receptor 1 ligand Pyridopyrazin... | 3 | 5 |
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1801305 ... | 2 | 0 |
Mitogen-activated protein kinase 9 and MAP kinase-activated pr... | 1 | 0 |
Mitogen-activated protein kinase 14 inhibitor N-ethyl-5-methyl... | 17 | 3 |
Mitogen-activated protein kinase 14 and Mitogen-activated prot... | 13 | 3 |
Fatty-acid amide hydrolase 1 inhibitor [5-(4-chlorophenyl)tria... | 2 | 2 |
Histone deacetylase 1 inhibitor (E)-N-hydroxy-3-[4-[[2-(1H-pyr... | 2 | 8 |
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... | 10 | 14 |
Renin inhibitor [2-[(3-fluoro-2-methylphenyl)methyl]-6-methyl-... | 2 | 1 |
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... | 2 | 8 |
Coagulation factor X inhibitor AGN-PC-0749BY family | 5 | 9 |
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... | 14 | 2 |
Histamine H3 receptor and Potassium voltage-gated channel subf... | 7 | 1 |
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... | 2 | 1 |
Histamine H3 receptor ligand SureCN2878688 family | 8 | 1 |
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... | 21 | 6 |
Coagulation factor X and Coagulation factor IX inhibitor pyraz... | 6 | 1 |
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... | 9 | 4 |
Rho-associated protein kinase 2 and Rho-associated protein kin... | 4 | 9 |
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... | 18 | 5 |
Histamine H1 receptor and Histamine H4 receptor ligand [4-[2-[... | 1 | 1 |
Transient receptor potential cation channel subfamily V member... | 2 | 1 |
Heat shock protein HSP 90-beta inhibitor N-[(9R)-4-(3H-imidazo... | 1 | 0 |
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family | 10 | 11 |
MAP kinase-activated protein kinase 2 inhibitor 4-fluoro-N-[4-... | 25 | 1 |
Coagulation factor X inhibitor SureCN8289965 family | 4 | 5 |
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... | 2 | 2 |
3-phosphoinositide-dependent protein kinase 1 and RAC-alpha se... | 10 | 4 |
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-0733AC family | 7 | 29 |
Delta-type opioid receptor ligand ethyl N-[3-[(R)-[4-[ethyl(me... | 2 | 6 |
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X3N ... | 1 | 7 |
Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... | 3 | 1 |
Mitogen-activated protein kinase 10 and Mitogen-activated prot... | 1 | 0 |
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... | 9 | 0 |
Dipeptidyl peptidase 4 and Cytochrome P450 3A4 inhibitor 6-[(3... | 10 | 0 |
Aurora kinase B and Cyclin-dependent kinase 1 inhibitor 7-cycl... | 3 | 16 |
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... | 5 | 3 |
Cell division cycle 7-related protein kinase and Protein DBF4 ... | 15 | 7 |
Mast/stem cell growth factor receptor Kit and Mitogen-activate... | 4 | 2 |
Casein kinase II subunit alpha and Serine/threonine-protein ki... | 1 | 5 |
Insulin-like growth factor 1 receptor and Mitogen-activated pr... | 3 | 4 |
Cell division cycle 7-related protein kinase and Dual specific... | 3 | 1 |
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... | 5 | 3 |
Protein kinase C theta type and Leucine-rich repeat serine/thr... | 1 | 1 |
Cytochrome P450 3A4 and Insulin-like growth factor 1 receptor ... | 24 | 57 |
Histamine H3 receptor ligand 1-[4-(1H-imidazol-5-ylmethyl)pipe... | 1 | 2 |
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... | 1 | 0 |
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... | 4 | 3 |
Platelet-derived growth factor receptor beta and Vascular endo... | 5 | 12 |
Dipeptidyl peptidase 4 inhibitor 2-[[2-[(3R)-3-aminopiperidin-... | 1 | 0 |
Epidermal growth factor receptor and Receptor tyrosine-protein... | 8 | 4 |
Mitogen-activated protein kinase 10 and Mitogen-activated prot... | 8 | 5 |
Aurora kinase A and Aurora kinase B inhibitor [4-[[7-cyclopent... | 6 | 0 |
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 8-[(3-meth... | 3 | 1 |
Protein kinase C theta type inhibitor (2-aminopyridin-3-yl)-[6... | 4 | 1 |
Glycogen synthase kinase-3 beta inhibitor N-[2-[4-(ethylsulfon... | 3 | 1 |
Glycogen synthase kinase-3 beta inhibitor N-[2-[4-(ethylsulfon... | 2 | 2 |
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... | 4 | 2 |
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... | 7 | 3 |
DNA gyrase subunit B inhibitor 5-[2-(ethylcarbamoyl)-4-[3-(tri... | 2 | 4 |
Lysine--tRNA ligase inhibitor N-[2-(2-piperazin-1-ylpyridin-4-... | 5 | 0 |
Somatostatin receptor type 3 and Potassium voltage-gated chann... | 3 | 0 |
Somatostatin receptor type 3 ligand tert-butyl 4-[(3R)-3-(5-ph... | 2 | 2 |
Activated CDC42 kinase 1 inhibitor N,N-dimethyl-4-[4-[[(2S)-ox... | 3 | 0 |
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... | 2 | 0 |
C-C chemokine receptor type 5 ligand AC1MHRXO family | 5 | 1 |
Growth hormone secretagogue receptor type 1 ligand SureCN36660... | 4 | 14 |
Renin inhibitor AGN-PC-073MLF family | 7 | 6 |
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152412 family | 8 | 0 |
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... | 4 | 1 |
Macrophage colony-stimulating factor 1 receptor and Cytochrome... | 10 | 0 |
Smoothened homolog inhibitor N-[4-methyl-3-(5-phenyl-1H-imidaz... | 1 | 0 |
Cathepsin K inhibitor CHEMBL2163360 family | 1 | 0 |
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... | 1 | 1 |
Probable G-protein coupled receptor 142 ligand (2S)-N-(2-oxo-5... | 2 | 1 |
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... | 11 | 2 |
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... | 12 | 4 |
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... | 12 | 0 |
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... | 17 | 0 |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... | 3 | 1 |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... | 5 | 6 |
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547496 f... | 2 | 1 |
Cathepsin K and Cathepsin S inhibitor 2-Cyano-pyrimidine, 17d ... | 5 | 9 |
Somatostatin receptor type 3 and Somatostatin receptor type 4 ... | 5 | 1 |
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206058 family | 5 | 0 |
Serine/threonine-protein kinase TBK1 inhibitor N-[3-[[5-cyclop... | 5 | 0 |
P2X purinoceptor 7 inhibitor SureCN109432 family | 10 | 28 |
P2X purinoceptor 7 inhibitor SureCN113576 family | 2 | 1 |
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[6-[2-(trif... | 1 | 0 |
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... | 11 | 4 |
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... | 3 | 0 |
Melanocortin receptor 4 ligand AGN-PC-076AMO family | 17 | 8 |
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... | 6 | 0 |
5-hydroxytryptamine receptor 2B ligand SureCN1299437 family | 6 | 7 |
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... | 11 | 10 |
CGMP-dependent protein kinase inhibitor SureCN14561191 family | 4 | 0 |
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... | 1 | 0 |
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... | 3 | 4 |
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... | 5 | 1 |
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor (3R)-... | 4 | 12 |
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-chloro... | 2 | 0 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 2 | 0 |
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... | 12 | 3 |
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... | 3 | 0 |
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... | 2 | 0 |
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... | 16 | 0 |
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... | 10 | 1 |
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... | 4 | 1 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 1 | 1 |
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... | 9 | 2 |
Calcitonin gene-related peptide type 1 receptor ligand N-[2-(7... | 16 | 0 |
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... | 2 | 8 |
Orexin receptor type 2 and Orexin receptor type 1 ligand SureC... | 2 | 0 |
C-C chemokine receptor type 5 ligand N-[3-[4-[3-cyclohexyl-5-(... | 5 | 4 |
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... | 4 | 0 |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-[4... | 1 | 1 |
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... | 2 | 3 |
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... | 2 | 1 |
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... | 2 | 14 |
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family | 3 | 0 |
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... | 3 | 0 |
Disintegrin and metalloproteinase domain-containing protein 17... | 10 | 4 |
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... | 3 | 0 |
RAF proto-oncogene serine/threonine-protein kinase and Serine/... | 4 | 3 |
Disintegrin and metalloproteinase domain-containing protein 17... | 4 | 0 |
Macrophage colony-stimulating factor 1 receptor and Mast/stem ... | 27 | 4 |
Metabotropic glutamate receptor 2 ligand 8-(2,5-difluorophenyl... | 6 | 2 |
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... | 9 | 2 |
Epidermal growth factor receptor and Receptor tyrosine-protein... | 3 | 1 |
Glycogen synthase kinase-3 beta inhibitor GSK-3beta Inhibitor ... | 1 | 0 |
Prothrombin inhibitor 2-[4-methyl-5-[[[2-[6-methyl-2-oxo-3-(2-... | 1 | 0 |
Macrophage colony-stimulating factor 1 receptor and Receptor-t... | 2 | 0 |
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... | 3 | 0 |
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... | 2 | 22 |
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... | 11 | 5 |
Matrilysin and Stromelysin-1 inhibitor (2R)-N-[(1S)-1-(1H-benz... | 3 | 0 |
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... | 5 | 0 |
Vasopressin V2 receptor and Vasopressin V1a receptor ligand Su... | 2 | 1 |
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... | 3 | 2 |
Epidermal growth factor receptor and Receptor tyrosine-protein... | 5 | 8 |
Thromboxane-A synthase inhibitor 6-chloro-3-(4-imidazol-1-ylbu... | 12 | 21 |
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... | 2 | 0 |
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... | 3 | 0 |
Mitogen-activated protein kinase 13 and Mitogen-activated prot... | 4 | 2 |
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... | 1 | 3 |
Tripeptidyl-peptidase 2 inhibitor (2S)-2-amino-1-[(2S)-5-chlor... | 1 | 0 |
Coagulation factor X inhibitor SureCN1652469 family | 2 | 1 |
Nitric oxide synthase, inducible inhibitor N-[(4-chlorophenyl)... | 2 | 1 |
Serine/threonine-protein kinase Chk1 inhibitor CHIR-124 family | 1 | 0 |
Serine/threonine-protein kinase B-raf inhibitor 1-[2-[[4-[2-cy... | 2 | 0 |
Corticotropin-releasing factor receptor 1 and Corticotropin-re... | 2 | 1 |
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... | 5 | 1 |
Gonadotropin-releasing hormone receptor ligand SureCN3275214 f... | 5 | 0 |
Cell division cycle 7-related protein kinase inhibitor Pyrrolo... | 2 | 6 |
Epidermal growth factor receptor ligand (E)-5-[4-(3-bromoanili... | 11 | 0 |
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... | 12 | 7 |
Cathepsin S and Cathepsin K inhibitor 2-cyano-N-[(2R)-1-phenyl... | 2 | 0 |
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RDJ family | 15 | 1 |
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... | 3 | 0 |
Gonadotropin-releasing hormone receptor and 5-hydroxytryptamin... | 2 | 0 |
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... | 7 | 2 |
Adenosine receptor A1 and Adenosine receptor A3 ligand CHEMBL4... | 2 | 0 |
Cyclin-dependent kinase 2 inhibitor SureCN3549598 family | 3 | 1 |
B1 bradykinin receptor ligand AGN-PC-077LWO family | 2 | 0 |
Transient receptor potential cation channel subfamily V member... | 3 | 2 |
Nitric oxide synthase, inducible and Nitric oxide synthase, br... | 2 | 0 |
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(4-py... | 9 | 0 |
Mast/stem cell growth factor receptor Kit and Tyrosine-protein... | 4 | 1 |
Platelet-derived growth factor receptor beta and Fibroblast gr... | 10 | 0 |
Cannabinoid receptor 1 ligand AGN-PC-077JWI family | 7 | 1 |
Aurora kinase A and Aurora kinase B inhibitor N-[(3E)-3-[5-(mo... | 3 | 2 |
Melanin-concentrating hormone receptor 1 ligand SureCN3834858 ... | 2 | 1 |
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... | 2 | 0 |
Dipeptidyl peptidase 4 inhibitor SureCN5776796 family | 1 | 0 |
Egl nine homolog 1 inhibitor 2-[(1,6-diphenylimidazo[4,5-c]pyr... | 1 | 5 |
Platelet-derived growth factor receptor beta and Fibroblast gr... | 2 | 1 |
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (3... | 1 | 1 |
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... | 3 | 0 |
Tyrosine-protein kinase Lck inhibitor (3S)-3-[(1S)-1-[[4-(benz... | 14 | 0 |
Mitogen-activated protein kinase 1 and Aurora kinase A inhibit... | 16 | 3 |
LIM domain kinase 2 inhibitor 3-[[(cyanoamino)-[(2S)-2-methyl-... | 6 | 0 |
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... | 4 | 0 |
Sonic hedgehog protein and Cytochrome P450 2C9 inhibitor AGN-P... | 1 | 0 |
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R96X family | 7 | 1 |
Tyrosine-protein kinase Lck and Tyrosine-protein kinase Lyn in... | 1 | 0 |
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... | 1 | 3 |
Cannabinoid receptor 2 ligand [(4S,4aR,8aS)-4-hydroxy-4-phenyl... | 1 | 0 |
Nitric oxide synthase, inducible and Nitric oxide synthase, br... | 1 | 4 |
Glycogen synthase kinase-3 beta inhibitor SureCN13987027 family | 1 | 0 |
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... | 1 | 2 |
Tyrosine-protein kinase JAK1 and Non-receptor tyrosine-protein... | 1 | 0 |
Aromatase and Beta-lactamase inhibitor N-(3-Imidazol-1-yl-prop... | 1 | 1 |
C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[3-(4-fluorop... | 1 | 0 |
Glycogen synthase kinase-3 beta inhibitor SureCN3535776 family | 1 | 0 |
Nonstructural protein 1 and Lysine-specific demethylase 4E inh... | 2 | 1 |
Thromboxane-A synthase inhibitor AGN-PC-00OGRA family | 1 | 0 |
Statistics of CFAM Database |
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes. |
How to cite our database |
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
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Last update by |
2014.08.29
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