CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10222
Family Name Serine/threonine-protein kinase pim-1 and Serine/threonine-protein kinase pim-2 inhibitor N-(2-methoxyphenyl)-6-(1H-1,2,4-triazol-5-yl)thieno[3,2-c]quinolin-4-amine family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00393210 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase pim-1 and Serine/threonine-protein kinase pim-2 Binder Superfamily 4
Class Class 4769

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 5
Calmodulin-domain protein kinase 1 and Tyrosine-protein kinase... 5 5
TGF-beta receptor type-1 ligand N-(4-methoxyphenyl)-3-(6-methy... 5 2
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 3
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 4 9
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 2
Hepatocyte growth factor receptor and Cytochrome P450 3A4 liga... 5 2
ALK tyrosine kinase receptor and Nucleophosmin ligand N-[2-[2-... 5 0
Activated CDC42 kinase 1 and Tyrosine-protein kinase Lck inhib... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00400522 CHEMBL2017352 Bioactive N-(4-methoxyphenyl)-6-(1H-1,2,4-triazol-5-yl)thieno[3,2-c]quinolin-4-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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