CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10224
Family Name Tyrosine-protein kinase SYK and Tyrosine-protein kinase ITK/TSK inhibitor 3-[(3E)-3-(5-ethoxy-6-fluorobenzimidazol-2-ylidene)-1,2-dihydropyrazol-4-yl]-1,1-diethylurea family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00400524 Functional Category Bioactive
Superfamily cAMP and Prelamin-A/C Binder Superfamily 3
Class Class 862

Cousin Family NamesSeedsMembers
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
Metabotropic glutamate receptor 5 ligand SureCN4297614 family 2 5
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Cyclin-dependent kinase 1 and Receptor tyrosine-protein kinase... 2 3
Rho-associated protein kinase 2 inhibitor SureCN1519463 family 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00400524 CHEMBL2017551 Bioactive 3-[(3E)-3-(5-ethoxy-6-fluorobenzimidazol-2-ylidene)-1,2-dihydropyrazol-4-yl]-1,1-diethylurea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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