CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1023
Family Name Beta-secretase 1 inhibitor SureCN8293614 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00318554 Functional Category Bioactive
Superfamily Beta-secretase 1 and Cathepsin B Binder Superfamily
Class Class 3128

Cousin Family NamesSeedsMembers
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Beta-secretase 1 Inhibitor GSK-188909 Family 16 11
Beta-secretase 1 inhibitor SureCN8292705 family 7 6
Beta-secretase 1 inhibitor N-[(1S,2S)-1-[(2R)-4-benzylsulfonyl... 2 0
Pol polyprotein inhibitor 2-[(2R,3S)-3-[[(2R)-3-(benzenesulfin... 15 15
Beta-secretase 1 and Cathepsin B inhibitor SureCN4666465 family 9 4
Beta-secretase 1 inhibitor 1-N-[(1R,2S)-1-[(2R,4S)-4-butoxypip... 5 1
Beta-secretase 1 and Cathepsin B inhibitor 3-chloro-N-[(2S)-1-... 2 0


External ID

Functional Category

Molecule Name

CFAMM00318555 CHEMBL1097351 Bioactive N-[(1S,2S)-1-[(2R)-4-(5-chlorothiophen-2-yl)sulfonylpiperazin-2-yl]-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl]-3-[(2R)-2-(methoxymethyl)pyrrolidine-1-carbonyl]-5-methylbenzamide
CFAMM00318554 CHEMBL1097333 Bioactive SureCN8293614

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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