CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10231
Family Name Cholecystokinin receptor type A ligand 6-[2-[2-(cyclohexylmethyl)piperidin-1-yl]-2-oxoethyl]-4-(1H-indol-3-ylmethyl)-1-phenyl-4H-[1,2,4]triazolo[3,4-d][1,5]benzodiazepin-5-one family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00400575 Functional Category Bioactive
Superfamily Insulin-like growth factor 1 receptor and Insulin receptor Binder Superfamily
Class Class 195

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 16
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-07RDWA fa... 1 4
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Smoothened homolog inhibitor SureCN1091571 family 2 2
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 10 1
Cholecystokinin receptor type A ligand AGN-PC-09M5EH family 1 7
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 4 4
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 15 7
Coagulation factor X inhibitor AGN-PC-0749BY family 5 9
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 9 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 5 3
Cyclin-dependent kinase 2 and Serine/threonine-protein kinase ... 2 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 16 5
Growth hormone secretagogue receptor type 1 ligand SureCN36800... 14 42
Growth hormone secretagogue receptor type 1 ligand SureCN36660... 4 14
Renin inhibitor AGN-PC-073MLF family 7 6
Renin inhibitor AGN-PC-002JXB family 14 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 2 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 2 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (3... 1 1


External ID

Functional Category

Molecule Name

CFAMM00400571 CHEMBL2017832 Bioactive (4S)-4-(2H-indazol-3-ylmethyl)-6-[2-[2-(2-methoxyethyl)piperidin-1-yl]-2-oxoethyl]-1-phenyl-4H-[1,2,4]triazolo[3,4-d][1,5]benzodiazepin-5-one
CFAMM00400575 CHEMBL2017828 Bioactive 6-[2-[2-(cyclohexylmethyl)piperidin-1-yl]-2-oxoethyl]-4-(1H-indol-3-ylmethyl)-1-phenyl-4H-[1,2,4]triazolo[3,4-d][1,5]benzodiazepin-5-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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