CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1024
Family Name Beta-secretase 1 inhibitor 1-N-[(1S,2S)-3-(3,5-difluorophenyl)-1-hydroxy-1-[(2R)-4-pyridin-4-ylsulfonylpiperazin-2-yl]propan-2-yl]-5-methyl-3-N,3-N-dipropylbenzene-1,3-dicarboxamide family
No. of Seeds 2 No. of Other Members 16
Family Centroid CFAMM00318560 Functional Category Bioactive
Superfamily Integrin beta-3 Inhibitor L-746233 Superfamily
Class Class 2080

Cousin Family NamesSeedsMembers
Pol polyprotein inhibitor AC1LAHQ9 family 8 15
Beta-secretase 1 and Beta-secretase 2 inhibitor SureCN5930118 ... 15 30
Beta-secretase 1 and Cathepsin B inhibitor SureCN14347937 family 4 1
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-(butyl... 2 4
Pol polyprotein inhibitor 169168-47-2 family 4 0
Prothrombin inhibitor N-[(2S)-3-(4-aminophenyl)-1-[4-(2-fluoro... 1 0
Prothrombin inhibitor N-[(2S)-3-(4-aminophenyl)-1-[4-(2-fluoro... 7 4
Prothrombin inhibitor N-[(1S)-2-[4-(2-fluoroethyl)piperidin-1-... 5 0
Prothrombin inhibitor 2-[(3S)-4-[4-(2-fluoroethyl)piperidin-1-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00318560 CHEMBL1097334 Bioactive 1-N-[(1S,2S)-3-(3,5-difluorophenyl)-1-hydroxy-1-[(2R)-4-pyridin-4-ylsulfonylpiperazin-2-yl]propan-2-yl]-5-methyl-3-N,3-N-dipropylbenzene-1,3-dicarboxamide
CFAMM00318573 CHEMBL1097350 Bioactive N-[(1S,2S)-3-(3,5-difluorophenyl)-1-hydroxy-1-[(2R)-4-pyridin-2-ylsulfonylpiperazin-2-yl]propan-2-yl]-3-[(2R)-2-(methoxymethyl)pyrrolidine-1-carbonyl]-5-methylbenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27272 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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