CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10253
Family Name Calcitonin gene-related peptide type 1 receptor ligand 2-[(7-methyl-1H-indazol-5-yl)methyl]-4-[4-(2-oxo-5-phenyl-1H-imidazol-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00400708 Functional Category Bioactive
Superfamily Calcitonin gene-related peptide type 1 receptor and Cytochrome P450 2D6 Ligand BMS-694153 Superfamily
Class Class 843

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 19 12
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 3
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 2
Serine/threonine-protein kinase 17A and Myosin light chain kin... 3 7
Serine/threonine-protein kinase mTOR inhibitor AGN-PC-093LHN f... 3 2
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
Calcitonin gene-related peptide type 1 receptor ligand 2-[(7-m... 2 1
Calcitonin gene-related peptide type 1 receptor ligand 3-[1-[4... 5 3
Calcitonin gene-related peptide type 1 receptor ligand N-[2-(7... 5 3
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 2 0
Vascular endothelial growth factor receptor 2 and Angiopoietin... 14 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN14402832 ... 6 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 1
Rho-associated protein kinase 2 inhibitor 2-[(3S,4R)-4-(4-fluo... 9 0
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 4 1
Serine/threonine-protein kinase Chk1 inhibitor SureCN4298966 f... 10 1
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 1 0
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 2 0
Calcitonin gene-related peptide type 1 receptor ligand SureCN2... 11 0
Calcitonin gene-related peptide type 1 receptor ligand [(2R)-3... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00400709 CHEMBL2018508 Bioactive 2-[(7-methyl-1H-indazol-5-yl)methyl]-4-[4-(2-oxo-1H-quinolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione
CFAMM00400708 CHEMBL2018507 Bioactive 2-[(7-methyl-1H-indazol-5-yl)methyl]-4-[4-(2-oxo-5-phenyl-1H-imidazol-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione
CFAMM00400710 CHEMBL2018509 Bioactive 1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-2-[(7-methyl-1H-indazol-5-yl)methyl]-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]butane-1,4-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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