CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10260
Family Name Peroxisome proliferator-activated receptor alpha and Peroxisome proliferator-activated receptor gamma ligand EHA family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00261046 Functional Category Bioactive
Superfamily Prostaglandin D2 receptor and 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Binder Superfamily
Class Class 2976

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Renin Inhibitor CP-305202 Family 9 30
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Acetylcholinesterase Inhibitor Lysicamine Family 2 8
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 5
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Acetylcholinesterase and Cholinesterase inhibitor (2Z)-5-metho... 4 23
Cellular tumor antigen p53 inhibitor CHEMBL1395699 family 1 30
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-3-... 8 3
Inosine-5'-monophosphate dehydrogenase 2 inhibitor 7-methoxy-2... 7 1
Coagulation factor X and Trypsin-1 inhibitor AGN-PC-0759OR family 4 7
NS5B protein inhibitor AGN-PC-00A17Z family 1 23
Serine/threonine-protein kinase B-raf inhibitor furan-based co... 6 3
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 5 12
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [5-(o... 4 4
Prostaglandin D2 receptor and Prostaglandin E2 receptor EP2 su... 2 0
NS5B protein inhibitor AC1O5AET family 3 1
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Integrase inhibitor (Z)-4-[1-[(4-fluorophenyl)methyl]-5-methox... 1 0
Peroxisome proliferator-activated receptor delta and Peroxisom... 3 17
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Cytosolic phospholipase A2 inhibitor AGN-PC-00BH8R family 6 13
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 5
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Potassium voltage-gated channel subfamily H member 2 and 5-hyd... 2 2
Peroxisome proliferator-activated receptor delta and Peroxisom... 1 1
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4
Seprase and Prolyl endopeptidase inhibitor N-[2-[(2S)-2-cyanop... 1 3
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 4 1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 3
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 7 1
Cannabinoid receptor 1 ligand (4-hydroxynaphthalen-1-yl)-[1-(2... 2 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 4 0
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 1 6
Cysteinyl leukotriene receptor 1 ligand 2-[2-[5-[[3-[(E)-2-(6,... 1 8
DNA-dependent protein kinase catalytic subunit inhibitor 2-mor... 1 4
Histamine H1 receptor and Alpha-1B adrenergic receptor ligand ... 1 4
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 6 5
Histamine H1 receptor and Histamine H2 receptor ligand SureCN6... 1 3
Histamine H1 receptor and Histamine H2 receptor ligand SureCN5... 3 6
Glutamate receptor 2 and Glutamate receptor 4 ligand SureCN828... 1 0
Cytosolic phospholipase A2 inhibitor SureCN3681683 family 3 0
Aldose reductase inhibitor [1-(3,5-difluoro-4-hydroxyphenyl)py... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27619 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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