CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10269
Family Name Cholinesterase and Acetylcholinesterase inhibitor 5-hydroxy-7-methoxy-4-oxo-N-[10-(1,2,3,4-tetrahydroacridin-9-ylamino)decyl]chromene-2-carboxamide;hydrochloride family
No. of Seeds 5 No. of Other Members 19
Family Centroid CFAMM00400842 Functional Category Bioactive with Natural Product
Superfamily Acetylcholinesterase and Cholinesterase Binder Superfamily 2
Class Class 3421

Cousin Family NamesSeedsMembers
Multidrug resistance-associated protein 1 Inhibitor Biricodar ... 6 40
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Vascular endothelial growth factor receptor 2 Ligand E 7080 Fa... 7 17
Vascular endothelial growth factor receptor 2 Ligand PF-003372... 1 4
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
MO15-related protein kinase Pfmrk Inhibitor WR-289010 Family 2 506
Oxytocin receptor and Vasopressin V1a receptor Ligand L-372662... 31 23
Renin Inhibitor CP-305202 Family 9 30
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 1 18
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Muscarinic acetylcholine receptor M2 and Acetylcholinesterase ... 4 24
Acetylcholinesterase and Muscarinic acetylcholine receptor M2 ... 2 7
Vascular endothelial growth factor receptor 2 ligand 7-(6-acet... 2 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 8 12
Acetylcholinesterase and Butyrylcholinesterase inhibitor [3-[[... 3 68
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N... 8 10
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 21
Butyrylcholinesterase and Acetylcholinesterase inhibitor AGN-P... 9 24
Cholinesterase and Acetylcholinesterase inhibitor 4-oxo-N-[9-(... 11 13
Acetylcholinesterase and Cholinesterase inhibitor N-[10-[(6-ch... 6 0
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Cholinesterase and Acetylcholinesterase inhibitor tacrine deri... 10 0
Acetylcholinesterase and Cholinesterase inhibitor 5-methoxy-7-... 1 18
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 1 0
Cysteinyl leukotriene receptor 1 ligand 4-oxo-7-[[3-(quinolin-... 4 17
Substance-P receptor ligand SureCN2139814 family 7 7
Substance-P receptor ligand AGN-PC-00FIT5 family 3 11
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(6aR... 1 0
ATP-binding cassette sub-family G member 2 inhibitor 5-[(4-bro... 1 1
Tyrosine-protein kinase ABL1 inhibitor N-(5-bromopyridin-2-yl)... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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