CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10280
Family Name Protease inhibitor AC1O53DF family
No. of Seeds 8 No. of Other Members 1
Family Centroid CFAMM00400991 Functional Category Bioactive
Superfamily Protease and Cathepsin D Binder Superfamily
Class Class 721

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] A inhibitor hydrazine antide... 1 1
Cystic fibrosis transmembrane conductance regulator and Anocta... 12 74
P2X purinoceptor 7 inhibitor N-[[2-chloro-3-(trifluoromethyl)p... 2 20
C-C chemokine receptor type 5 ligand N-[(1S)-3-[(3aS,6aR)-5-(3... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00400984 CHEMBL21082 Bioactive ethyl (E,4S)-4-[[(2S)-2-[[(2S)-3,3-dimethyl-2-[(5-methyl-1,2-oxazole-3-carbonyl)amino]butanoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
CFAMM00400990 CHEMBL279448 Bioactive AC1O55R3
CFAMM00400989 CHEMBL291277 Bioactive AC1O54SC
CFAMM00400988 CHEMBL291276 Bioactive AC1O54SF
CFAMM00400987 CHEMBL327058 Bioactive ethyl (E,4S)-4-[[(2R,5S)-2-[(4-fluorophenyl)methyl]-7-methyl-5-[(5-methyl-1,2-oxazole-3-carbonyl)amino]-4-oxooctanoyl]amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate
CFAMM00400986 CHEMBL289920 Bioactive AC1O54S9
CFAMM00400985 CHEMBL20210 Bioactive Rupintrivir
CFAMM00400991 CHEMBL20636 Bioactive AC1O53DF

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

25040 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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