CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10285
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-2-[4-[1-[cyclopropyl-(4-pyridin-2-ylcyclohexyl)amino]ethenyl]phenyl]-1,1,1-trifluoropropan-2-ol family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00401057 Functional Category Bioactive
Superfamily Cannabinoid receptor 2 and Cannabinoid receptor 1 Binder Superfamily 9
Class Class 3108

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Doxylamine Family 2 91
Citric Acid family 2 58
PF-4136309 family 16 27
D(2) dopamine receptor and D(3) dopamine receptor Ligand L-741... 9 73
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 13 26
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 5 69
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapol Family 3 41
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 18 17
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 4 7
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
C-C chemokine receptor type 2 ligand N-[2-[[(3R)-1-(4-hydroxy-... 4 0
Glucocorticoid receptor ligand 1,1,1-trifluoro-2-[(1-methyl-3,... 3 4
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 5 8
Platelet-activating factor receptor ligand SureCN9852997 family 1 1
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 5
Nociceptin receptor and Potassium voltage-gated channel subfam... 3 9
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 1,1,1... 12 3
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 7
Aromatase inhibitor AGN-PC-075MRV family 1 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00401057 CHEMBL2021495 Bioactive (2R)-2-[4-[1-[cyclopropyl-(4-pyridin-2-ylcyclohexyl)amino]ethenyl]phenyl]-1,1,1-trifluoropropan-2-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27520 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543