CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10296
Family Name Muscarinic acetylcholine receptor M3 ligand 3-[8-methyl-8-(2-phenylmethoxyethyl)-8-azoniabicyclo[3.2.1]octan-3-yl]-2,2-diphenylpropanenitrile;iodide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00401123 Functional Category Bioactive
Superfamily Substance-P receptor and Muscarinic acetylcholine receptor M3 Binder Superfamily
Class Class 100

Cousin Family NamesSeedsMembers
Opioid receptor ligand synthetic opioid methadone analog Dextr... 2 108
Histamine H1 receptor Ligand Clemastine Family 5 76
Histamine H1 receptor Ligand Diphenhydramine Family 5 75
Alpha-1B adrenergic receptor ligand Morpholine derivative Phen... 4 152
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Cocain... 13 136
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Muscarinic acetylcholine receptor Ligand Umeclidinium Family 7 50
Substance-P receptor Ligand L-733060 Family 19 71
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Substance-P receptor ligand (2S)-3-[[3,5-bis(trifluoromethyl)p... 1 4
Substance-P receptor ligand 4-[[3,5-bis(trifluoromethyl)phenyl... 2 1
Substance-P receptor ligand AGN-PC-03NGZP family 3 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0
Substance-P receptor ligand SureCN8415737 family 3 4
Sodium-dependent dopamine transporter and Sigma non-opioid int... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-0793IB... 2 0
Substance-P receptor ligand (3aR,4R,5S,7aS)-5-[(1R)-1-[3,5-bis... 4 0
Histamine H1 receptor and 5-hydroxytryptamine receptor 2A liga... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand (4aR,... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00401123 CHEMBL2023765 Bioactive 3-[8-methyl-8-(2-phenylmethoxyethyl)-8-azoniabicyclo[3.2.1]octan-3-yl]-2,2-diphenylpropanenitrile;iodide
CFAMM00401122 CHEMBL2021997 Bioactive 3-[8-methyl-8-(3-phenylmethoxypropyl)-8-azoniabicyclo[3.2.1]octan-3-yl]-2,2-diphenylpropanenitrile;bromide
CFAMM00401121 CHEMBL490244 Bioactive AGN-PC-00RZYY

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27260 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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