CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10297
Family Name Aurora kinase A and Aurora kinase B inhibitor N-[6-methyl-3-[1-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]pyrazol-4-yl]imidazo[1,2-a]pyrazin-8-yl]-3-(piperidin-1-ylmethyl)-1,2-thiazol-5-amine family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00334276 Functional Category Bioactive
Superfamily Aurora kinase A and Aurora kinase B Binder Superfamily 5
Class Class 3234

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M6EM fa... 11 88
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09QGL9 fa... 23 5
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M82N fa... 13 0
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M46L fa... 2 7
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M770 fa... 2 0
Serine/threonine-protein kinase Chk1 and Cyclin-A2 inhibitor S... 1 1
Aurora kinase A and Aurora kinase B inhibitor N-[6-methyl-3-[1... 1 0
Aurora kinase A and Aurora kinase B inhibitor [4-[[7-cyclopent... 6 0
Casein kinase II subunit alpha and Homeodomain-interacting pro... 5 0
Casein kinase II subunit alpha inhibitor N-[5-[[3-cyano-7-(cyc... 3 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
Somatostatin receptor type 3 and Potassium voltage-gated chann... 3 3
Tyrosine-protein kinase ABL1 and Abelson tyrosine-protein kina... 3 0
Casein kinase II subunit alpha inhibitor N-[5-[[3-cyano-7-[(1-... 9 0
Aurora kinase B and Aurora kinase A inhibitor N-(furan-2-ylmet... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

25231 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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