CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10309
Family Name Dihydrofolate reductase and Bifunctional dihydrofolate reductase-thymidylate synthase inhibitor AGN-PC-00SITS family
No. of Seeds 6 No. of Other Members 3
Family Centroid CFAMM00373714 Functional Category Bioactive
Superfamily Dihydrofolate reductase and Microtubule-associated protein tau Binder Superfamily
Class Class 1503

Cousin Family NamesSeedsMembers
Acyl-CoA desaturase Inhibitor Isoxyl Family 5 62
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 12 44
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 11 12
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 0
Dihydrofolate reductase inhibitor 10-[3-(4-nitrophenoxy)propox... 1 1
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 4 19
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
Prostacyclin receptor ligand CAY10441 family 1 0
Dihydrofolate reductase inhibitor 4-[[4-(4,6-diamino-2,2-dimet... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45057 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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