CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10344
Family Name Platelet-derived growth factor receptor beta and Macrophage colony-stimulating factor 1 receptor ligand N-[3-[(dimethylamino)methyl]-5-methylphenyl]-2-[2-methoxy-4-(7-methoxyquinolin-4-yl)oxyphenyl]acetamide family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00330632 Functional Category Bioactive
Superfamily Vascular endothelial growth factor receptor 2 Binder Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Multidrug resistance protein Inhibitor Tariquidar Family 3 60
Vascular endothelial growth factor receptor 2 Ligand E 7080 Fa... 7 17
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Proto-oncogene tyrosine-protein kinase Src inhibitor SureCN525... 8 8
B2 bradykinin receptor ligand SureCN8516699 family 3 2
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 1
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
Disintegrin and metalloproteinase domain-containing protein 17... 2 5
B2 bradykinin receptor ligand SureCN6640854 family 7 4
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Metabotropic glutamate receptor 2 and Metabotropic glutamate r... 3 3
Cytochrome P450 11B2, mitochondrial and Cytochrome P450 11B1, ... 9 7
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 2
Platelet-derived growth factor receptor beta and Receptor-type... 6 5
Platelet-derived growth factor receptor beta and Macrophage co... 8 0
Platelet-derived growth factor receptor beta ligand N-(4,5-dim... 5 1
Platelet-derived growth factor receptor alpha and Mast/stem ce... 2 2
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[(1... 2 0
Vascular endothelial growth factor receptor 2 and Aurora kinas... 4 3
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 12 0
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Hepatocyte growth factor receptor ligand 1-(2-chlorophenyl)-N-... 14 8
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 11 7
Prothrombin and Coagulation factor X inhibitor N-[3-[(3-fluoro... 1 8
Serine/threonine-protein kinase Chk1 inhibitor SureCN4854955 f... 2 0
Vascular endothelial growth factor receptor 2 ligand 6-(6,7-di... 4 0
Vascular endothelial growth factor receptor 2 and Cytochrome P... 2 1
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 4 4
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 9 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 0
Leucyl-cystinyl aminopeptidase inhibitor SureCN988709 family 1 14


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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