CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1036
Family Name Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor 1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00170379 Functional Category Bioactive
Superfamily Cyclin-A2 and AMP deaminase 3 Binder Superfamily
Class Class 307

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
PHA848125 family 13 138
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Orexin receptor type 2 and Orexin receptor type 1 ligand [(7R)... 10 10
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 42
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-07ZE3... 6 1
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
Type-1 angiotensin II receptor ligand SureCN9527437 family 2 34
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
Adenosine receptor A1 ligand AGN-PC-07PMLW family 6 4
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-09M4U... 4 5
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Nuclear receptor ROR-gamma and Mitogen-activated protein kinas... 1 10
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 1 1
Mitogen-activated protein kinase 14 inhibitor N-ethyl-5-methyl... 17 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 13 3
Coagulation factor X inhibitor AGN-PC-0749BY family 5 9
Mitogen-activated protein kinase 14 inhibitor ethyl N-[4-[5-(m... 5 2
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 6 0
Metabotropic glutamate receptor 5 ligand 5-(4-fluorophenyl)-1,... 7 1
Tyrosine-protein kinase JAK2 inhibitor 4-[[8-(1-propan-2-ylpyr... 5 6
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Type-1 angiotensin II receptor ligand 2-ethyl-4-[[4-[2-(2H-tet... 2 0
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-07B2Q... 6 0
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-07RBL... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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