CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10377
Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-[2-[4-[[3-(trifluoromethyl)phenyl]methyl]piperidin-1-yl]ethyl]cyclohexyl]acetamide family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00401560 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 Inhibitor Denagliptin Superfamily
Class Class 1224

Cousin Family NamesSeedsMembers
Peripheral carotid chemoreceptor Ligand Doxapram Family 4 36
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 2 18
Substance-P receptor Ligand Vestipitant Family 14 137
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 3 12
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 11 6
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Melatonin receptor type 1A Ligand N-(2,3-dihydro-1h-phenalen-2... 8 13
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 3 1
Cellular tumor antigen p53 and Retinal dehydrogenase 1 inhibit... 1 4
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (2S... 16 24
C-C chemokine receptor type 3 ligand 1-(2,3-dimethyl-3a,7a-dih... 4 0
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 5
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 7 3
Substance-P receptor ligand (3S,4S)-N-[[3,5-bis(trifluoromethy... 8 9
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor (2... 3 10
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 4 1
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 9 1
Substance-P receptor ligand AGN-PC-073QYE family 6 11
C-C chemokine receptor type 2 ligand (1S,3R)-N-[[3-fluoro-5-(t... 22 27
Alpha-1A adrenergic receptor and Histamine H1 receptor ligand ... 13 1
Substance-P receptor and Potassium voltage-gated channel subfa... 5 1
Glucose-dependent insulinotropic receptor ligand (1-methylcycl... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00401563 CHEMBL2024512 Bioactive ethyl N-[4-[2-[4-[[3-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]ethyl]cyclohexyl]carbamate
CFAMM00401560 CHEMBL2024507 Bioactive N-[4-[2-[4-[[3-(trifluoromethyl)phenyl]methyl]piperidin-1-yl]ethyl]cyclohexyl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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