CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10390
Family Name Malonyl-CoA decarboxylase, mitochondrial inhibitor [4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-piperidin-1-ylmethanone family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00401638 Functional Category Bioactive
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 and Prelamin-A/C Binder Superfamily
Class Class 3272

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Haloperidol Family 5 53
B-lymphocyte antigen CD20 Inhibitor Bevacizumab+rituximab Family 1 5
Angiotensin-converting enzyme Inhibitor N-carboxymethyl-n-cycl... 2 24
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 9
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 5
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-[4-... 30 10
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 13 22
Delta-type opioid receptor and Kappa-type opioid receptor liga... 3 4
Malonyl-CoA decarboxylase, mitochondrial inhibitor 4-cyano-N-e... 1 2
Benzyl Alcohols and Derivatives Metabolite Secodemethylclausen... 1 1
2-bromo-N-[(2R)-2-hydroxy-2-phenylethyl]-N-methylbenzamide NP ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00401634 CHEMBL206852 Bioactive AGN-PC-00AZIH
CFAMM00401639 CHEMBL202689 Bioactive AGN-PC-00DVX2
CFAMM00401638 CHEMBL204287 Bioactive [4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-piperidin-1-ylmethanone
CFAMM00401637 CHEMBL380487 Bioactive N-(2-cyanoethyl)-N-ethyl-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzamide
CFAMM00401636 CHEMBL203835 Bioactive AGN-PC-00CMH7
CFAMM00401635 CHEMBL205506 Bioactive [4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-pyrrolidin-1-ylmethanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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