CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10391
Family Name Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-aminobutyric acid receptor subunit beta-3 ligand SureCN3996861 family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00401645 Functional Category Bioactive
Superfamily Cruzipain and Cationic trypsin Binder Superfamily
Class Class 667

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Farnesyltransferase beta subunit, putative Inhibitor Zarnestra... 10 56
Translocator protein Inhibitor Emapunil Family 7 89
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 13 55
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
Farnesyltransferase beta subunit, putative and Protein farnesy... 20 81
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 14 13
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 45
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Prothrombin inhibitor SureCN5856722 family 3 16
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Macrophage colony-stimulating factor 1 receptor and Cytochrome... 13 3
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 10
Survival motor neuron protein and Menin inhibitor CHEMBL132797... 1 1
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... 13 8
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
Signal transducer and activator of transcription 6 inhibitor A... 3 0
Fatty-acid amide hydrolase 1 inhibitor [5-(4-chlorophenyl)tria... 2 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 11 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 13 1
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 8-[(3-meth... 3 1
CGMP-dependent protein kinase inhibitor 1-[2-(4-fluorophenyl)-... 1 4
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 2
Translocator protein inhibitor CHEMBL2331870 family 2 0
CGMP-dependent protein kinase inhibitor SureCN14561191 family 4 0
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 3 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 1
Gonadotropin-releasing hormone receptor ligand SureCN3275214 f... 5 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 1 1
Metabotropic glutamate receptor 5 ligand 2-[4-(4-fluoro-3-meth... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00401643 CHEMBL202696 Bioactive SureCN4003734
CFAMM00401642 CHEMBL203877 Bioactive 2-[5-(7-ethyl-8-oxoimidazo[1,2-d][1,2,4]triazin-3-yl)-2-fluorophenyl]-5-fluorobenzonitrile
CFAMM00401641 CHEMBL206587 Bioactive SureCN3998212
CFAMM00401640 CHEMBL203186 Bioactive SureCN2643457
CFAMM00401646 CHEMBL205205 Bioactive SureCN3997669
CFAMM00401645 CHEMBL203211 Bioactive SureCN3996861
CFAMM00401644 CHEMBL206380 Bioactive SureCN3997965

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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