CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10427
Family Name Coagulation factor VII inhibitor 2-[(3E)-3-(5-carbamimidoyl-1,3-dihydrobenzimidazol-2-ylidene)-5-(5-chloro-2-hydroxyphenyl)-4-oxocyclohexa-1,5-dien-1-yl]butanedioic acid family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00401906 Functional Category Bioactive
Superfamily Coagulation factor VII and Urokinase-type plasminogen activator Binder Superfamily
Class Class 931

Cousin Family NamesSeedsMembers
JNJ-39439335 family 5 11
Plasminogen and Prothrombin Inhibitor 2-(2-hydroxy-phenyl)-1h-... 3 69
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 50 17
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 4 11
Plasma kallikrein and Coagulation factor VII inhibitor 2-[(3E)... 15 49
Serine/threonine-protein kinase Chk1 inhibitor SureCN6387344 f... 6 11
Coagulation factor VII inhibitor [3-[(5E)-5-(5-carbamimidoyl-1... 3 2
Coagulation factor X and Urokinase-type plasminogen activator ... 8 10
Coagulation factor VII and Tissue factor inhibitor 2-[3-(5-car... 3 2
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-07CR... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00401907 CHEMBL383639 Bioactive 2-[(3E)-5-(3-bromo-5-chloro-2-hydroxyphenyl)-3-(5-carbamimidoyl-1,3-dihydrobenzimidazol-2-ylidene)-4-oxocyclohexa-1,5-dien-1-yl]butanedioic acid
CFAMM00401906 CHEMBL206234 Bioactive 2-[(3E)-3-(5-carbamimidoyl-1,3-dihydrobenzimidazol-2-ylidene)-5-(5-chloro-2-hydroxyphenyl)-4-oxocyclohexa-1,5-dien-1-yl]butanedioic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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