CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1043
Family Name Leukotriene A-4 hydrolase inhibitor SureCN13809114 family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00318694 Functional Category Bioactive
Superfamily Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Duloxetine Superfamily
Class Class 286

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 2
Leukotriene A-4 hydrolase Inhibitor (r/s)-2-((4-phenoxyphenoxy... 7 18
Renin Inhibitor Ro-65-7219 Family 10 8
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
Leukotriene A-4 hydrolase inhibitor SureCN2108222 family 3 9
DNA-(apurinic or apyrimidinic site) lyase and Menin inhibitor ... 1 6
Prothrombin inhibitor SureCN6594996 family 7 8
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 13
5-hydroxytryptamine receptor 7 and D(2) dopamine receptor liga... 5 17
Dipeptidyl peptidase 4 inhibitor AGN-PC-014VUU family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00318696 CHEMBL578345 Bioactive (2R)-2-[[4-[(4-thiophen-3-ylphenyl)methyl]phenoxy]methyl]pyrrolidine
CFAMM00318694 CHEMBL1098531 Bioactive SureCN13809114

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27512 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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