CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10435
Family Name Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acid family
No. of Seeds 14 No. of Other Members 8
Family Centroid CFAMM00402117 Functional Category Bioactive
Superfamily Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Superfamily
Class Class 2020

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
B2 bradykinin receptor Ligand FR-173657 Family 44 180
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(4-ethox... 4 5
Integrin beta-3 and Integrin alpha-V inhibitor 2-(2,3-dihydro-... 13 1
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN2059024 f... 6 3
Melanin-concentrating hormone receptor 1 ligand N-[3-(2-aminoq... 4 1
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[5-methy... 4 5
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(4-fluo... 7 1
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(3,5-di... 1 0
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(2,6-di... 6 5
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-3-[4-[2-(1... 1 0
Metabotropic glutamate receptor 5 and Cytochrome P450 3A4 liga... 3 7
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5368289 f... 4 5
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5367895 f... 3 0
Peroxisome proliferator-activated receptor gamma and Cytochrom... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00402119 CHEMBL2030799 Bioactive (2S)-2-[(2-chloro-4-fluorobenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acid
CFAMM00402112 CHEMBL2031172 Bioactive (2S)-3-[4-[2-[6-(cyclopropylmethylamino)pyridin-2-yl]ethoxy]phenyl]-2-[(2,6-dichlorobenzoyl)amino]propanoic acid
CFAMM00402125 CHEMBL2031160 Bioactive (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl]propanoic acid
CFAMM00402118 CHEMBL2030800 Bioactive (2S)-2-[(2-chloro-6-fluorobenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acid
CFAMM00402117 CHEMBL2030807 Bioactive (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acid
CFAMM00402110 CHEMBL2031170 Bioactive (2S)-3-[4-[2-(6-aminopyridin-2-yl)ethoxy]phenyl]-2-[(2,6-dichlorobenzoyl)amino]propanoic acid
CFAMM00402123 CHEMBL2030970 Bioactive (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[6-[2-[6-(methylamino)pyridin-2-yl]ethoxy]pyridin-3-yl]propanoic acid
CFAMM00402109 CHEMBL2030961 Bioactive (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[3-fluoro-4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acid
CFAMM00402122 CHEMBL2031168 Bioactive (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-[2-(1-methyl-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-6-yl)ethoxy]phenyl]propanoic acid
CFAMM00402121 CHEMBL2031169 Bioactive (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-[2-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-6-yl)ethoxy]phenyl]propanoic acid
CFAMM00402114 CHEMBL2030968 Bioactive (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[5-[2-[6-(methylamino)pyridin-2-yl]ethoxy]pyridin-2-yl]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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