CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10436
Family Name Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(4-fluoro-2-methylbenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acid family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00231516 Functional Category Bioactive
Superfamily Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Superfamily
Class Class 2020

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor gamma Ligand Piogli... 2 29
Histamine H1 receptor Ligand Mepyramine Family 5 65
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Neuromedin-K receptor Ligand 3-methoxy-n',2-diphenylquinoline-... 14 33
Neuromedin-K receptor and Substance-K receptor ligand 2-[2-phe... 2 2
Disintegrin and metalloproteinase domain-containing protein 17... 2 8
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(4-ethox... 4 5
Integrin beta-3 and Integrin alpha-V inhibitor 2-(2,3-dihydro-... 13 1
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
Survival motor neuron protein inhibitor CHEMBL1307497 family 1 2
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Pol polyprotein inhibitor 3-[[(4R,5S,6S,7R)-4,7-dibenzyl-3-(3,... 12 1
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Adenosine receptor A3 ligand AGN-PC-08WSLM family 5 22
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(dime... 2 2
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN2059024 f... 6 3
Integrin alpha-V and Integrin beta-5 inhibitor SureCN2491273 f... 11 10
Integrin beta-3 and Integrin alpha-V inhibitor (3S,7S)-7-hydro... 5 1
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[5-methy... 4 5
Prostaglandin D2 receptor 2 ligand 2-[1-[4-[(4-methoxybenzoyl)... 2 2
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(2,6-di... 14 8
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(3,5-di... 1 0
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-3-[4-[2-(1... 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Plasmepsin-2 and Cathepsin D inhibitor 4-[4-[[(2S,3S)-1-[[(3S,... 3 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-03OERH f... 1 0
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 12 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 19 11
Integrin beta-1 and Integrin alpha-5 inhibitor SureCN14453385 ... 5 0
Peroxisome proliferator-activated receptor gamma and Cytochrom... 1 1
Mitogen-activated protein kinase 14 and Dual specificity mitog... 2 4
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 3 1
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[(1-acetylpiperidin-4... 58 15
Cathepsin E and Cathepsin D inhibitor SureCN2530955 family 3 1
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1
Matrilysin and 72 kDa type IV collagenase inhibitor (3S,6R,7S)... 2 2
Prothrombin inhibitor AGN-PC-074I2Z family 2 1
Integrin beta-3 and Integrin alpha-V inhibitor SureCN244675 fa... 1 0
Farnesyl pyrophosphate synthase inhibitor [phosphono-[[4-(4-pr... 6 0
Sodium channel protein type 9 subunit alpha ligand N-[6-[4-(4-... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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