CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10449
Family Name Lysosomal Pro-X carboxypeptidase inhibitor [4-[2-(3-chloro-4-fluorophenyl)-5-methyl-1,2,4-triazol-3-yl]piperidin-1-yl]-[(1R,2R,4S)-2-(2,4-difluorophenyl)-4-(dimethylamino)-4-methylcyclopentyl]methanone family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00402280 Functional Category Bioactive
Superfamily Lysosomal Pro-X carboxypeptidase Binder Superfamily 3
Class Class 213

Cousin Family NamesSeedsMembers
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 2
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 3
Lysosomal Pro-X carboxypeptidase inhibitor N-[(1S)-1-(5,6-dich... 3 21
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 4 15
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
Lysosomal Pro-X carboxypeptidase inhibitor [(1R,2R,4S)-4-amino... 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00402280 CHEMBL2031584 Bioactive [4-[2-(3-chloro-4-fluorophenyl)-5-methyl-1,2,4-triazol-3-yl]piperidin-1-yl]-[(1R,2R,4S)-2-(2,4-difluorophenyl)-4-(dimethylamino)-4-methylcyclopentyl]methanone
CFAMM00402279 CHEMBL2031580 Bioactive [4-[2-(4-chloro-3-methylphenyl)-5-methyl-1,2,4-triazol-3-yl]piperidin-1-yl]-[(1R,2R,4S)-2-(2,4-difluorophenyl)-4-(dimethylamino)-4-methylcyclopentyl]methanone
CFAMM00402282 CHEMBL2031582 Bioactive [4-[2-(2,5-dichlorophenyl)-5-methyl-1,2,4-triazol-3-yl]piperidin-1-yl]-[(1R,2R,4S)-2-(2,4-difluorophenyl)-4-(dimethylamino)-4-methylcyclopentyl]methanone
CFAMM00402281 CHEMBL2031583 Bioactive [(1R,2R,4S)-4-amino-2-(2,4-difluorophenyl)-4-methylcyclopentyl]-[4-[2-(2,5-dichlorophenyl)-5-methyl-1,2,4-triazol-3-yl]piperidin-1-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

71883 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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