CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10454
Family Name Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S,3R)-2-[(1,3-benzoxazol-2-ylamino)methyl]-3-methylpiperidin-1-yl]-(2-methyl-5-phenyl-1,3-thiazol-4-yl)methanone family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00377491 Functional Category Bioactive
Superfamily Orexin receptor type 2 and Orexin receptor type 1 Binder Superfamily 4
Class Class 985

Cousin Family NamesSeedsMembers
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Arachidonate 5-lipoxygenase Inhibitor 5-methyl-n-phenylbenzo[d... 5 13
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25
Adenosine receptor A2b and Adenosine receptor A2a ligand AGN-P... 10 36
Adenosine receptor A2a and Adenosine receptor A2b ligand AGN-P... 4 2
Adenosine receptor A2b and Adenosine receptor A2a ligand AGN-P... 1 1
5-hydroxytryptamine receptor 3A ligand 2-[(3S)-3-ethylmorpholi... 10 18
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 1 14
Adenosine receptor A1 and Adenosine receptor A2b ligand AGN-PC... 3 2
Adenosine receptor A1 and Adenosine receptor A2b ligand AGN-PC... 1 0
Neuropeptides B/W receptor type 1 ligand [4-(1,3-benzoxazol-2-... 6 1
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1,3-benzoxazol... 3 4
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[(2S,5S)-5-(... 20 10
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 5 2
Cathepsin S and Cathepsin L1 inhibitor (2S)-2-(1,3-benzoxazol-... 1 9
Cathepsin S and Cathepsin L1 inhibitor SureCN5361439 family 2 4
5-hydroxytryptamine receptor 6 ligand SureCN3910449 family 3 15
Protein-cysteine N-palmitoyltransferase porcupine inhibitor N-... 5 2


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45057 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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