CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10457
Family Name Lysosomal Pro-X carboxypeptidase inhibitor [(1R,2R,4S)-4-amino-2-(2,4-difluorophenyl)-4-methylcyclopentyl]-[4-[2-(3-chloro-4-fluorophenyl)-5-methylpyrazol-3-yl]piperidin-1-yl]methanone family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00402327 Functional Category Bioactive
Superfamily Lysosomal Pro-X carboxypeptidase Binder Superfamily 3
Class Class 213

Cousin Family NamesSeedsMembers
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 5 22
Orexin receptor type 2 and Orexin receptor type 1 ligand AGN-P... 7 19
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 3 59
P2X purinoceptor 7 inhibitor N-[[2-chloro-3-(trifluoromethyl)p... 3 10
Glucocorticoid receptor ligand N-ethyl-2-fluoro-N-[3,3,3-trifl... 16 7
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 4
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 4 15
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
Lysosomal Pro-X carboxypeptidase inhibitor [4-[2-(3-chloro-4-f... 5 0
Cannabinoid receptor 1 ligand AGN-PC-07NHJ5 family 9 1
P2X purinoceptor 7 inhibitor SureCN1194877 family 1 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00402322 CHEMBL2031598 Bioactive [(1S,2S,4R)-4-amino-2-(2,4-difluorophenyl)-4-methylcyclopentyl]-[4-[2-(3-chloro-4-fluorophenyl)pyrazol-3-yl]piperidin-1-yl]methanone
CFAMM00402321 CHEMBL2031588 Bioactive [4-[2-(2,5-dichlorophenyl)-5-methylpyrazol-3-yl]piperidin-1-yl]-[(1R,2R,4S)-2-(2,4-difluorophenyl)-4-(dimethylamino)-4-methylcyclopentyl]methanone
CFAMM00402327 CHEMBL2031591 Bioactive [(1R,2R,4S)-4-amino-2-(2,4-difluorophenyl)-4-methylcyclopentyl]-[4-[2-(3-chloro-4-fluorophenyl)-5-methylpyrazol-3-yl]piperidin-1-yl]methanone
CFAMM00402320 CHEMBL2031589 Bioactive [(1R,2R,4S)-4-amino-2-(2,4-difluorophenyl)-4-methylcyclopentyl]-[4-[2-(2,5-dichlorophenyl)-5-methylpyrazol-3-yl]piperidin-1-yl]methanone
CFAMM00402326 CHEMBL2031590 Bioactive [4-[2-(3-chloro-4-fluorophenyl)-5-methylpyrazol-3-yl]piperidin-1-yl]-[(1R,2R,4S)-2-(2,4-difluorophenyl)-4-(dimethylamino)-4-methylcyclopentyl]methanone
CFAMM00402325 CHEMBL2031595 Bioactive [4-[2-(3-chloro-4-fluorophenyl)pyrazol-3-yl]piperidin-1-yl]-[(1S,2S,4S)-2-(2,4-difluorophenyl)-4-(dimethylamino)-4-methylcyclopentyl]methanone
CFAMM00402324 CHEMBL2031597 Bioactive [(1S,2S,4S)-4-amino-2-(2,4-difluorophenyl)-4-methylcyclopentyl]-[4-[2-(3-chloro-4-fluorophenyl)pyrazol-3-yl]piperidin-1-yl]methanone
CFAMM00402323 CHEMBL2031596 Bioactive [4-[2-(3-chloro-4-fluorophenyl)pyrazol-3-yl]piperidin-1-yl]-[(1S,2S,4R)-2-(2,4-difluorophenyl)-4-(dimethylamino)-4-methylcyclopentyl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

72597 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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