CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10459
Family Name Histamine H3 receptor ligand 2-(4-piperidin-1-ylpiperidin-1-yl)-5-quinolin-8-yl-1,3,4-thiadiazole family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00402329 Functional Category Bioactive
Superfamily Histamine H3 receptor and Survival motor neuron protein Binder Superfamily 3
Class Class 1250

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Metabotropic glutamate receptor 5 Ligand 3-(1-pyridin-2-yl-1h-... 3 6
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 2 7
Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... 4 0
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 5 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[6-... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00402329 CHEMBL2031605 Bioactive 2-(4-piperidin-1-ylpiperidin-1-yl)-5-quinolin-8-yl-1,3,4-thiadiazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26239 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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