CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10464
Family Name Arachidonate 5-lipoxygenase-activating protein inhibitor 5-[2-[(1S,3R,4S)-3-phenyl-3-bicyclo[2.2.1]heptanyl]-4-(quinolin-2-ylmethoxy)phenyl]-3H-1,3,4-oxadiazol-2-one family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00402346 Functional Category Bioactive
Superfamily Arachidonate 5-lipoxygenase-activating protein Binder Superfamily
Class Class 3578

Cousin Family NamesSeedsMembers
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Arachidonate 5-lipoxygenase inhibitor (2E)-2-[2-butyl-1-[4-(qu... 1 12
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 12 3
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[[4... 7 4
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[[2... 4 4
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 3 5
Cysteinyl leukotriene receptor 1 ligand 4-oxo-7-[[3-(quinolin-... 4 17


External ID

Functional Category

Molecule Name

CFAMM00402344 CHEMBL2031661 Bioactive 5-[2-(3-methyl-1-phenylcyclobutyl)-4-(quinolin-2-ylmethoxy)phenyl]-3H-1,3,4-oxadiazol-2-one
CFAMM00402350 CHEMBL2031658 Bioactive 5-[2-[(1S,3S,4S)-3-(3-methoxyphenyl)-3-bicyclo[2.2.1]heptanyl]-4-(quinolin-2-ylmethoxy)phenyl]-3H-1,3,4-oxadiazol-2-one
CFAMM00402343 CHEMBL2031660 Bioactive 5-[2-(3,3-dimethyl-1-phenylcyclobutyl)-4-(quinolin-2-ylmethoxy)phenyl]-3H-1,3,4-oxadiazol-2-one
CFAMM00402349 CHEMBL2031659 Bioactive 5-[2-[(1S)-2,2-dimethyl-1-phenylpropyl]-4-(quinolin-2-ylmethoxy)phenyl]-3H-1,3,4-oxadiazol-2-one
CFAMM00402348 CHEMBL2031657 Bioactive 5-[2-[(1S,3S,4S)-3-phenyl-3-bicyclo[2.2.1]heptanyl]-4-(quinolin-2-ylmethoxy)phenyl]-3H-1,3,4-oxadiazol-2-one
CFAMM00402347 CHEMBL2031647 Bioactive 5-[2-[(1S,3R,4S)-3-phenyl-3-bicyclo[2.2.1]heptanyl]-4-(quinolin-2-ylmethoxy)phenyl]-3H-1,3,4-oxadiazole-2-thione
CFAMM00402346 CHEMBL2031646 Bioactive 5-[2-[(1S,3R,4S)-3-phenyl-3-bicyclo[2.2.1]heptanyl]-4-(quinolin-2-ylmethoxy)phenyl]-3H-1,3,4-oxadiazol-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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